Main description:

The seventh edition of this textbook has been fully revised and to provide students with the most recent knowledge and advances in the field of pharmacology.  

Beginning with an overview of general principles, the following sections discuss drugs for disorders found in different systems of the body.

New topics have been added to this edition including an overview of the autonomic nervous system, sympathomimetic drugs, ischemic heart disease, drugs in ophthalmology and more.

Chapters include case studies helping bridge the gap between theoretical knowledge and practical application, as well as multiple choice questions and answers to assist revision and test knowledge.

Written by recognised experts from the USA and Australia, this comprehensive guide is highly illustrated with more than 400 images, tables and figures.

Key Points

• Comprehensive guide to most recent advances in field of pharmacology for medical students


• Fully revised, new edition with many new topics


• Chapters include case studies and multiple choice questions and answers


• Previous edition published in 2003 (9780781737623)

Contents:

Section 1: General Principles of Pharmacology

1 Introduction to Pharmacology

2 Mechanisms of Drug Action

3 Drug Absorption and Distribution 

4 Metabolism and Excretion of Drugs  

5 Pharmacokinetics

6 Drug Metabolism and Disposition in Pediatric and Gerontological Stages of Life

7 Principles of Toxicology 

8 Ethical Issues in Pharmaceutical Research

Section 2: Drugs Affecting the Autonomic System

9 Introduction to the Autonomic Nervous System

10 Sympathomimetic Drugs and Other Adrenoceptor Agonists

11 Adrenoceptor Antagonists

12 Cholinomimetic Drugs

13 Cholinergic Antagonists and Ganglionic Blocking Drugs

Section 3: Drugs Affecting the Cardiovascular System

14 The Renin–Angiotensin System and Other Vasoactive Substances

15 Diuretic Drugs

16 Calcium Channel Blockers

17 Anticoagulant, Antiplatelet, and Thrombolytic Drugs 

18 Hypocholesterolemic Drugs and Coronary Heart Disease

19 Antihypertensive Drugs

20 Drugs for Heart Failure

21 Treatment of Ischemic Heart Disease

22 Antiarrhythmic Drugs

Section 4: Drugs Affecting the Central Nervous System

23 Introduction to Central Nervous System Pharmacology 

24 Opioid Analgesics

25 Benzodiazepines

26 General Anesthesia: Intravenous and Inhalational Agents

27 Local Anesthetics

28 Agents Affecting Neuromuscular Function and Disease

29 Antiepileptic Drugs

30 Sedative–Hypnotic Drugs

31 Mood Disorders: Drugs Used in Depression, Anxiety, and Bipolar Disorder

32 Antipsychotic Drugs

33 Central Nervous System Stimulants

34 Drugs Used in Neurodegenerative Disorders

35 Current Issues in Substance Abuse and Treatment

Section 5: Drugs Used in Inflammatory and Other Select Disorders

36 Introduction to Inflammation and Glucocorticoids

37 Non-Steroidal Antiinflammatory Drugs and Acetaminophen

38 Disease-Modifying Antirheumatic Drugs

39 Histamine and Histamine Antagonists

40 Immunomodulating Drugs

Section 6: Chemotherapy

41 Introduction to Chemotherapy

42 Inhibitors of Cell Wall and Cell Membrane Function

43 Inhibitors of Nucleic Acid Synthesis and Function

44 Inhibitors of Protein Synthesis

45 Drugs Used in Tuberculosis and Leprosy 

46 Antiviral Drugs

47 Drugs for Human Immunodeficiency Virus

48 Antifungal Drugs

49 Antiprotozoal Drugs

50 Anthelmintic Drugs 

51 The Rational Basis for Cancer Chemotherapy

52 Antineoplastic Agents

53 Pharmacogenetics and Pharmacogenomics

Section 7: Drugs Affecting the Endocrine System

54 Hypothalamic and Pituitary Gland

55 Adrenocortical Hormones and Drugs Affecting the Adrenal Cortex

56 Estrogens, Progestins, and SERMs

57 Uterine Stimulants and Relaxants

58 Androgens, Antiandrogens, and Anabolic Steroids

59 Drugs Used in the Treatment of Erectile Dysfunction

60 Thyroid and Antithyroid Drugs

61 Insulin, Glucagon, Amylin, Incretins, and Other Compounds Used to Manage Diabetes Mellitus

62 Drugs for Treating Asthma and Chronic Obstructive Pulmonary Disease

63 Drugs Used in Gastrointestinal Disorders

64 Parathyroid Hormone, Calcitonin, Vitamin D, Vitamin D Analogs and Other Compounds Related to Bone and Mineral Metabolism

65 Drugs for Dermatological Disorders

66 Drugs Used in Ophthalmology

67 Drugs for Gout

68 Vitamins

69 Herbal Medicine