Published October, 2011
By David W. Weiss
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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The references brought in support of a given point are often intentionally varied,including both reports of original work and reviews, very recent observa tions and contributions that gave initial impetus to investigations, in an attempt to exemplify the pertinent literature;

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Published October, 2011
By U.H. Koszinowski, H. Hengel and U. H. Koszinowski
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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Since the first observations of viral interference with antigen presentation in the MHC class-I pathway, the field has advanced to a detailed analysis.

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Published October, 2011
By Ernst-L. Winnacker, Michael Famulok, Chi-Huey Wong and M. Famulok
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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The essence of combinatorial chemistry or techniques involving "molecular diversity" is to generate enormous populations of molecules and to exploit appropriate screening techniques to isolate active components contained in these libraries.

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Published October, 2011
By Steven Tracy, Nora M. Chapman, Brian W.J. Mahy and Brian W. J. Mahy
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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Within the next few years, it was apparent that this and other similar viruses were not polioviruses but were indeed a new group of viruses, viruses that by the mid- 1950s had been found to be commonly associated with pediatric inflammatory heart disease.

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Published October, 2011
By L. Du Pasquier, G.W. Litman, Louis Du Pasquier and Gary W. Litman
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop ment of the principal concepts that created the foundation of what now is the broad field of immunology.

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Published October, 2011
By Peter K. Vogt, Frank J. III Rauscher and Frank J. Rauscher
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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Regulation of gene expression at the level of transcription is one of the major determinants of proper cellular proliferation and differentiation. This volume gives insights into how normal programs of gene expression can be subverted by the action of single transcription factors resulting in a specific tumor type.

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Published September, 2011
By Michael B. Kastan
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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KASTAN Cancer is a disease resulting from alterations of cellular genes which cause phe notypic changes in somatic cells. The vast majority of genes which are altered in the cancer cells are not transmitted through the germ line, but rather become abnormal in somatic cells sometime during the lifetime of the individual.

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Published September, 2011
By H. Wagner
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses.

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Published September, 2011
By Fritz Melchers and Michael Potter
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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The papers in this book were presented at the 14th Mechanisms in B-cell Neoplasia meeting that was held in Bethesda, Maryland October 21-23, 1996. , for their outstanding organizational assistance. With 2 Figures . . . . . . . . . . . . . . . . . . . . . . . .

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Published September, 2011
By Ursula Gunthert and Walter Birchmeier
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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