Main description:

Integrates biochemical, molecular, and cellular health and disease processes into one essential text!

Biochemistry, Cell and Molecular Biology, and Genetics: An Integrated Textbook by Zeynep Gromley and Adam Gromley is the first to cover molecular biology, cell biology, biochemistry (metabolism), and genetics in one comprehensive yet concise resource. Throughout the book, these topics are linked to other basic medical sciences, such as pharmacology, physiology, pathology, immunology, microbiology, and histology, for a truly integrated approach.

Key Highlights

Easy-to-read text enhances understanding of underlying molecular mechanisms of disease
Nearly 500 illustrations and tables help reinforce chapter learning objectives
Textboxes throughout make connections with other preclinical disciplines
End of unit high-order clinical vignette questions with succinct explanations help integrate basic science topics with clinical medicine

This textbook provides a robust review for medical students preparing for courses as well as exams. Dental, pharmacy, physician's assistant, nursing, and graduate students in pre-professional/bridge programs will also find this a beneficial learning tool.

This book includes complimentary access to a digital copy on https://medone.thieme.com.

Contents:

Part I

1. Anatomy of the Cell and Organelles

2. DNA Replication, Gene Mutations, and Repair

3. Transcription and Regulation of Transcription

4. Translation and Regulation of Translation

Part II

5. Cytoskeleton

6. Protein Sorting, Modifications, and Intracellular Traffic

7. Membrane Transport

8. Extracellular Matrix

9. Cell Adhesion and Membrane Junctions

10. Signal Transduction

11. Cell Cycle and Control of the Cell Cycle

12. Stem Cells and Hematopoiesis

13. Cell Injury, Apoptosis, and Necrosis

14. Hallmarks of Cancer and Cancer Biology

15. Molecular Principles of Cancer Treatments and Therapies

Part III

16. Enzymes and Enzyme Kinetics

17. Regulation of Enzyme Activity

18. Structure and Function of Proteins

19. Molecular and Biological Techniques

20. Plasma Proteins and the Diagnostic Use of Enzymes

Part IV

21. Digestion and Absorption of Carbohydrates

22. Glycolysis

23. Metabolism of Fructose, Galactose and the Pentose Phosphate Pathway (HMP Shunt)

24. Glycogen Metabolism and Regulation

25. Gluconeogenesis

26. Pyruvate Dehydrogenase and Tricarboxylic Acid (TCA) Cycle

27. Electron Transport Chain (ETC) and Oxidative Phosphorylation

28. Oxygen Toxicity and Antioxidants

29. Oxidation of Fatty Acids and Ketogenesis

30. Acid Base Chemistry and Acid Base Disorders

31. Glucose Homeostasis and Maintenance of Blood Glucose Concentrations

Part V

32. Digestion and Absorption of Proteins

33. Nitrogen Metabolism

34. Amino Acid Metabolism

35. Amino Acid Derivatives

36. Porphyrin Heme Metabolism and Iron Homeostasis

37. Nucleotide Metabolism

38. Vitamins in One-Carbon Metabolism

Part VI

39. Digestion and Absorption of Lipids

40. Synthesis of Fatty Acids and Triacylglycerols

41. Metabolism of Membrane Lipids and Lipid Derivatives

42. Cholesterol Metabolism

43. Blood Lipoproteins

44. Steroid Hormones and Vitamin D

45. Nutrition and Metabolism

46. Vitamins and Minerals

Part VII

47. DNA Packaging and Meiosis

48. Cytogenetics: Chromosomal Basis of Human Diseases

49. Single Gene Disorders: Autosomal Dominant and Recessive Inheritance

50. Sex-Linked and Non-Traditional Modes of Inheritance

51. Population Genetics

52. Genomic Imprinting and Epigenetics

53. Gene Interactions and Multifactorial Inheritance

54. Personalized Medicine

55. Developmental Genetics

56. Cancer Genetics