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Antidepressants
New Pharmacological Strategies
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Main description:

In this book, leading-edge investigators offer effective strategies to improve current antidepressive therapies and suggest molecular, biological, and genetic approaches that will lead to the development of novel antidepressants. The contributors' critical reviews and commentaries illuminate our understanding of the mechanism(s) responsible for antidepressant action. The book's goal is to move beyond current biogenic amine-based concepts and therapies to the development of new and improved antidepressants that are more effective and have a more rapid onset than current.


Contents:

Strategies to Optimize the Antidepressant Action of Selective Serotonin Reuptake Inhibitors, Luz Romero, Josep M. Casanovas, Ildefons Hervas, Roser Cortes, and Francesc Artigas. Antidepressant Properties of Specific Serotonin-Noradrenaline Reuptake Inhibitors, Michael Briley and Chantal Moret. 5-HT Moduline: Novel Therapeutic Strategy for Antidepressant Action, Gilles Fillion, Laure Seguin, Olivier Massot, Jean-Claude Rousselle, Marie-Paule Fillion, Isabelle Cloez-Tayarani, Brigitte Grimaldi, Jean-Christophe Seznec, and Nicole Prudhomme. Reversible Inhibitors of Monoamine Oxidase A (RIMAs): Where Can We Go from Here? Vivette Glover. Calcium Channel Antagonists in Mood Disorders, Olgierd Pucilowski. Functional NMDA Antagonists: A New Class of Antidepressant Agents, Ramon Trullas. Is an Adaptation of NMDA Receptors an Obligatory Step in Antidepressant Action? Nuo-Yu Huang, Richard T. Layer, and Phil Skolnick. NMDA Receptors and Affective Disorders, Ian A. Paul. The Potential Contribution of Sigma Receptors to Antidepressant Actions, Brian E. Leonard. A Role for CREB in Antidepressant Action, Ronald S. Duman, Masashi Nibuya, and Vidita A. Vaidya. Antidepressants: Beyond the Synapse, S. Paul Rossby and Fridolin Sulser. Animal Models to Detect Antidepressants: Are New Strategies Necessary to Detect New Agents? Paul Willner and Mariusz Papp. Molecular Strategies to Novel Antidepressant Discovery, Steven M. Paul, Xin Wu, Yanbin Liang, and Edward I. Ginns. Index.


PRODUCT DETAILS

ISBN-13: 9781617370489
Publisher: Springer (Humana Press Inc.)
Publication date: November, 2010
Pages: 268
Weight: 522g
Availability: Available
Subcategories: Neuroscience
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