The Annual Update compiles reviews of the most recent developments in experimental and clinical intensive care and emergency medicine research and practice in one comprehensive reference book. The chapters are written by well recognised experts in these fields. The book is addressed to everyone involved in internal medicine, anaesthesia, surgery, paediatrics, intensive care and emergency medicine.
Part I. Precision medicine.- Precision delivery in critical care: balancing prediction and personalization.- Precision medicine in the ICU: identifying opportunities and overcoming barriers.- Part II. Acute Respiratory Failure - ARDS.- Acute respiratory failure in the oncologic patient: new era, new issues.- Universal low tidal volume: early initiation of low tidal volume ventilation in patients with and without ARDS.- Recruitment maneuvers and higher PEEP, the so-called open lung concept, in patients with ARDS: rationale, limitations and indications.- ARDS in obese patients: specificities and management.- Part III. Extracorporeal Respiratory Support.- ECMO after EOLIA: the evolving role of extracorporeal support in ARDS.- Physiological and technical consideration of extracorporeal CO2 removal.- Part IV. Cardiac arrest.- Cardiac arrest in the ICU.- Targeted temperature management after cardiac arrest: where are we now?.- Part V. Cardiac Function.- Left diastolic function in critically ill mechanically ventilated patients.- The effects of disease and treatment on ventriculo-arterial coupling: implications for long term care.-Part VI. Shock.- Lactate in critically ill patients: at the crossroad between perfusion and metabolism.- Mechanical circulatory support devices for cardiogenic shock: state of the Art.- Sodium thiosulfate: a new player for circulatory shock and ischemia/reperfusion injury?.- Part VII. Hemodynamic Monitoring.- Continuous non-invasive monitoring of cardiac output and lung volume based on CO2 kinetics.- Should we abandon measuring SvO2 or ScvO2 in septic patients?.- Perioperative hemodynamic monitoring: MERCI to predict economic impact.- The pulmonary artery catheter in the management of the high risk surgical patient: an irreplaceable tool!.- Part VIII. Intravenous Fluids.- Resuscitation fluid choices to preserve the endothelial glycocalyx.-Should albumin be the colloid of choice for fluid resuscitation in hypovolemic patients?.- What the intensive care physician should know about the transurethral resection (TUR) syndrome.- Relationship between central venous pressure and acute kidney injury in critically ill patients.- Fluid management in acute kidney injury.- Part IX. Altered Renal Function.- New insights into renal microcirculation in sepsis-induced acute kidney injury.- Atypical sepsis-associated acute kidney injury.- Latest developments in perioperative acute kidney injury.- Diagnostic implications of creatinine and urea metabolism in critical illness.- Renal replacement therapy during septic renal dysfunction.- Acid-base disorders and regional citrate anticoagulation with continuous renal replacement therapy.- Acute kidney injury and delirium: kidney-brain cross-talk.- Part X. The Neurological Patient.- Brain ultrasound in the non-neurocritical care setting.- Brain fog: Are clearer skies on the horizon? A review on perioperative neurocognitive disorders.- Uncovering consciousness in unresponsive ICU patients: technical, medical and ethical considerations.- Part XI. Infection and Antibiotics.- From influenza-induced acute lung injury to multiorgan failure.- Multidrug resistant Gram-negative bacteria in community-acquired pneumonia.- Lights and shadows of antibiotics recently approved and in advanced development for critically ill patients.- Target-controlled infusion in the ICU: an opportunity to optimize antibiotic therapy.- Antimicrobial stewardship in sepsis.- Part XII. Sepsis.- Heterogeneity in sepsis: new biological evidence with clinical applications.- The role of mitochondrial dysfunction in sepsis: what is new?.- Potential harm related to fluid resuscitation in sepsis.- Extracorporeal cytokine removal in septic shock.- Part XIII. Iron Metabolism.- Transferrin as a possible treatment of anemia of inflammation in the critically ill.- Iron metabolism: an emerging therapeutic target in critical illness.- Part XIV. Extremes of Age.- Functional impairments in pediatric critical illness survivors: current knowledge and future directions.- Care of the critically older adult: An update and look for the future.- Part XV. Patient Comfort.- Inhaled sedation and reflection systems.- Intensity matched algorithm for comfort in intensive care patients: I-MAC ICU.- Sleep and circadian rhythm in critical illness.- Part XVI. Medical Education.- Social media in critical care: entering an exciting new era.