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Age-Related Macular Degeneration, Third Edition
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Main description:

The value of Age-Related Macular Degeneration has stood the test of time, but progress in both basic and clinical ophthalmology has been relentless, mandating the need for an updated book. This second edition focuses on the pathophysiology and the epidemiology of age-related macular degeneration (AMD), the clinical features and management of dry and wet AMD, imaging techniques, and medical therapy for both non-neovascular AMD and neovascular AMD. It describes both clinically validated and experimental therapies as well as rehabilitation technology, and presents strategies to prevent the progression of non-exudative AMD. Results from current clinical trials are also included.

New chapters in this edition cover:

  • Genetics and treatment

  • Oxidative stress and its relation to the pathophysiology of AMD and CNV (choroidal neovascularization—a common symptom of wet AMD)

  • Polypoidal choroidal vasculopathy

  • Microperimetry and psychophysical testing and ways to track geographic atrophy progression

  • Non-VEGF pathways

  • Retinal stem cells


Pathophysiology and Epidemiology of AMD
Histopathology of Age-Related Macular Degeneration
Immunology of Age-Related Macular Degeneration
Genetics of Age-Related Macular Degeneration
Choroidal Neovascularization: VEGF Pathways
Risk factors for Age-Related Macular Degeneration and Choroidal Neovascularization
Oxidative Stress
Clinical Features of AMD
Geographic Atrophy
Non-Neovascular Age-Related Macular Degeneration
Neovascular Age-Related Macular Degeneration
Polypoidal Choroidal Vasculopathy
Variants of Neovascular Age-related Macular Degeneration: Type 3 Neovascularization (Intra-retinal Neovascularization or Retinal Angiomatous Proliferation)
Imaging Techniques for the Clinical Evaluation of AMD
Fluorescein Angiography in Age-related Macular Degeneration
Indocyanine Green Angiography in Age-Related Macular Degeneration
Optical Coherence Tomography in the Evaluation of Age-Related Macular Degeneration
How to Analyze OCT images for Management of Neovascular AMD
Fundus Autofluorescence Imaging in Age-Related Macular Degeneration
Microperimetry and Psychophysical Testing to Aid in Determination of Progression of AMD
Current and Experimental Medical Treatment for Neovascular AMD
Laser Photocoagulation for Choroidal Neovascularization
Anti-VEGF drugs and Clinical trials
Non-VEGF Related Anti-Angiogenesis Pathways for Treatment of AMD
Radiation Therapy Treatment in Age-Related Macular Degeneration
Combination Therapy for AMD
Photodynamic Therapy for Neovascular AMD
Photocoagulation of AMD-Associated CNV Feeder Vessels
Macular Translocation and Other Surgical Treatments
Current and Experimental Medical Treatment for Non-Neovascular AMD and Geographic Atrophy
Prophylactic Treatment: The AREDS Study Results
Visual Cycle Modulation
Cellular Transplantation for Advanced Age-Related Macular Degeneration
Novel Therapeutic Interventions: Stem Cell
Rehabilitation of the Eye
Clinical Considerations for Visual Rehabilitation
Visual Prostheses for Age-Related Macular Degeneration
Development of Research Protocols in AMD
Clinical Research Trials


ISBN-13: 9781841849492
Publisher: Taylor & Francis (CRC Press)
Publication date: November, 2012
Pages: 404
Weight: 3g
Availability: Available
Subcategories: General, Ophthalmology and Optometry


Jennifer I. Lim, M.D. is a professor of ophthalmology, Department of Ophthalmology; Director of the Retina Service; Marion H. Schenk, Esq. Chair in Ophthalmology for Research of the Aging Eye, at the University of Illinois at Chicago.

Dr Lim has contributed to over 90 courses, and has published over 200 academic papers, contributed to over 20 book chapters and published 4 books in total. She has given over 150 presentations at scientific meetings and has been invited to over 130 lectures/visiting professorships. Dr Lim is a reviewer for a number of academic journals including the American Journal of Ophthalmology, Retina, and the British Journal of Ophthalmology. She is currently a committee member for the Macula Society, American Society of Retinal Specialists, and American Academy of Ophthalmology.

Recent Awards:

•Marion H. Schenk, Esq., Chair in Ophthalmology for Research of the Aging Eye, 2010
•Best Doctors in America 2010-2011 (initially and continuously selected since 1994)


Average Rating 

"Professor Lim has brought us up to the moment. We owe her and her collaborators a vote of thanks and a vote of confidence. Hopefully, the march of time, with its inexorable acquisition of new knowledge, will mandate the need for yet another edition. For the time being, however, this Third Edition of Age-Related Macular Degeneration does its job commendably and effectively." Morton F. Goldberg, M.D., Director Emeritus The Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore, Maryland USA