This book describes the biochemistry and genetics of aerobic degradation of hydrocarbons and lipids by bacteria and yeasts, as well as the functional genomics of the best-known microorganisms involved in these processes. It forms part of the Handbook of Hydrocarbon and Lipid Microbiology Series, a definitive resource of current knowledge on the diverse aspects of the interactions of microbes with hydrocarbons and lipids. Chapters are mainly focused on the new discoveries of recent years. It is aimed to scientists and others interested in different aspects of the microbiology of hydrocarbons.
-Preface to the volume -Introduction: Diversity and Common Principles in Enzymatic Activation of Hydrocarbons 1. BIOCHEMISTRY OF AEROBIC DEGRADATION OF HYDROCARBONS-Introduction: energetic and Other Quantitative Aspects of Microbial Hydrocarbon Utilization-Physiology and Biochemistry of the Aerobic Methane Oxidizing Bacteria-Biochemistry and Molecular Biology of Methane Monooxygenase-Enzymes for Aerobic Degradation of Alkanes in Bacteria-Enzymes for Aerobic Degradation of Alkanes inYeasts-Aerobic Degradation of Aromatic Hydrocarbons-Aerobic Degradation of Aromatic Hydrocarbons: Enzyme Structures and Catalytic Mechanisms-Oxidative Inactivation of Ring-Cleavage Extradiol Dioxygenases: Mechanism and Ferredoxin-Mediated Reactivation-Aerobic Degradation of Chloroaromatics-Aerobic Degradation of Halogenated Aliphatics-Structure-Function Relationships and Engineering of Haloalkane Dehalogenases-Aerobic degradation of gasoline ether oxygenates 2. GENETICS AND FUNCTIONAL GENOMICS OF AEROBIC DEGRADATION OF HYDROCARBONS (THE PARADIGMS)-Genetic features of Methylotrophs-Genetic Features and Regulation of n-Alkane Metabolism in bacteria-Genetic Features and Regulation of n-Alkane Metabolism in Yeasts-A Genomic View of the catabolism of short chain alkanes Florin Musat-Genetics and Molecular Features of Bacterial Dimethylsulfoniopropionate (DMSP) and Dimethylsulfide (DMS) Transformations-Genetics and ecology of isoprene degradation-Transcriptional Control of the TOL Plasmid Pathways-Genetics of Biphenyl Biodegradation and Co-Metabolism of PCBs"/div>-Genomic View of Mycobacterial High Molecular Weight Polycyclic Aromatic Hydrocarbon Degradation-A genomic view of the catabolism of aromatic compounds in Pseudomonas-Phylogenomics of Aerobic Bacterial Degradation of Aromatics-Experimental Evolution of Novel Regulatory Activities in Response to Hydrocarbons and Related Chemicals-Rational Construction of Bacterial Strains with New/Improved Catabolic Capabilities for the Efficient Breakdown of Environmental Pollutants-Functional Gene Diversity, Biogeography, Dynamics (all hydrocarbons) 3. BIOCHEMISTRY OF AEROBIC DEGRADATION OF LIPIDS -Lipid degradation - lipid cycles-Lipolytic Enzymes from Bacteria-Metabolism of steroids 4. GENETICS AND FUNCTIONAL GENOMICS OF AEROBIC DEGRADATION OF LIPIDS 5. GLOBAL ACTIVITIES, GLOBAL CONSEQUENCES OF AEROBIC DEGRADERS-Global aerobic degradation of hydrocarbons in marine systems-Global aerobic degradation of hydrocarbons in freshwater systems-Global aerobic degradation of hydrocarbons in terrestrial systems-Global Consequences of the Microbial Production and Consumption of Inorganic and Organic Sulfur Compounds-Potential for Microbial Interventions to Reduce Global Warming