A picture says more than a thousand words. This is something that we all know to be true. Imaging has been important since the early days of medicine and bi- ogy, as seen in the anatomical studies of Leonardo Da Vinci or Andreas Vesalius. More than 100 years ago, the ?rst noninvasive imaging technologies, such as K- rad Roentgen’s X-ray technology,were applied to the medical ?eld—and while still crude—revolutionized medical diagnosis. Today, every patient will be exposed to some kind of advanced imaging technology such as medical resonance imaging, computed tomography or four-dimensional ultrasound during their lifetime. Many diseases, such as brain tumors, are initially diagnosed solely by imaging, and most of the surgical planning relies on the patient imagery. 4D ultrasound is available to expecting parents who wish to create unique early memories of the new baby, and it may soon be used for the morphometric diagnosis of malformations that may one day be treatable—inutero! Light and electron microscopy are unequal brethren, which have contributed to most of our knowledge about the existence and organization of cells, tissues and microorganisms. Every student of biology or medicine is introduced to the fascinating images of the microcosm. New advances have converted these im- ing technologies, which were considered by many to be antiquated, into powerful tools for research in systems biology and related ?elds.
The past years experienced a boom in the development of novel imaging technologies, used in biological research as well as in clinical diagnosis.
First book to provide a complete overview of advanced imaging technologies
Introduction to all various aspects of advanced imaging in the medical and biological field
Since the invention of X-Ray technology by Konrad Roentgen in 1895, non-invasive imaging technologies are part of the medical and biological tool kit. Today, quite a number of non-invasive imaging technologies exist, from 4-dimensional Ultrasound to Computer Tomography. Almost every individual is subjected to one or more of these technologies during their lifetime. Destructive imaging approaches such as light- and electron microscopy have benefitted from the development of computing algorithms and digital imaging, making them more and more valuable for the study of biological and medical phenomena.
Not only is the number of imaging technologies increasing rapidly, at the same time the strategies and algorithms for image analysis are becoming more and more sophisticated. This book attempts for the first time to provide an overview of the major approaches to biological and medical imaging, the strategies for image analysis and the creation of models, which are based on the results of image analysis. This sets the book aside from the usual monographs, which introduce the reader only to a single technology.
Given the broad range of topics covered, this book provides an overview of the field, which is useful for a wide audience, from physicians and biologists to readers who would like to know more about the technology, which is used to derive diagnoses of diseases today.
Preface.- Imaging Technologies.- Micro-computed Tomography – Steven K. Boyd.- Advanced Experimental Magnetic Resonance Imaging – Ursula I. Tuor.- Freehand 3D Ultrasound Calibration: A Review – Po-Wei Hsu, Richard W. Prager, Andrew H. Gee, Graham M. Treece.- Laser Scanning – 3D Analysis of Biological Surfaces – Mattew W. Tocheri.- Optical Coherence Tomography – Technique and Applications – Jakob B. Thomsen, Birgit Sander, Mette Mogensen, Lars Thrane, Thomas M. Jørgensen, Gregor B.E. Jemec, Peter E. Andersen.- Mass Spectrometry-based Tissue Imaging – Carol E. Parker, Derek Smith, Detlev Suckau, Christoph H. Borchers.- Imaging and Evaluating Live Tissues at the Microscopic Level – John R. Matyas.- Ultrastructural Imaging: Imaging and Probing the Structure and Molecular Make-up of Cells and Tissues – Matthias Amrein.- Optical Projection Tomography – James Sharpe.- Imaging in Cancer Diagnosis –Jörg Peter.- Software.- Volume Visualization Using Virtual Reality – Anton H.J. Koning.- Surface Modeling – Andrei L. Turinsky.- CAVEman, an Object-Oriented Model of the Human Body – Christoph W. Sensen, Jung Soh.- Image-based Finite Element Analysis – Steven K. Boyd.- Geometric Morphometrics and the Study of Development – Benedikt Hallgrímsson, Julia C. Boughner, Andrei Turinsky, Trish E. Parsons, Cairine Logan, Christoph W. Sensen.- Applications.- Imaging in Audiology - Jos J. Eggermont.- Applications of Molecular Imaging with Magnetic Resonance – Linda B. Andersen, Richard Frayne.- Genomic Data Visualization - The Bluejay System – Jung Soh, Paul M.K. Gordon, Christoph W. Sensen.- Anatomical Imaging and Post-Genomic Biology - Benedikt Hallgrímsson and Nicholas Jones.- Functional Measures of Therapy Based on Radiological Imaging – David Dean, Nathan Cross, Davood Varghai, Nancy L. Oleinick, Chris A Flask.- Index.