Main description:

Reviewing the most current literature, this text is a guide to medical decision-making regarding the diagnosis and treatment of patients with acromegaly. The scope of the book is comprehensive, covering all relevant facets of acromegaly, beginning with a history of the disorder and a review of the somatotrophic axis. Etiology is then discussed, including growth hormone secreting pituitary adenomas and other neuroendocrine tumors. Subsequent chapters present imaging modalities and diagnosis via radiology and clinical findings, as well as comorbid symptoms such as sleep apnea, musculoskeletal considerations, cardiovascular disorders, cancer and diabetes. Both medical and surgical management chapters describe each in detail, including radiotherapy, transsphenoidal surgery, somatostatin analogues and dopamine agonists. Concluding chapters present long-term follow-up as well as an extended selected patient story detailing life with the disease.
Bringing together the latest in endocrinologic and neurosurgical evidence and practice, Acromegaly will be the go-to resource for this challenging condition for years to come.

Contents:

1 Growth Hormone-secreting Pituitary Adenomas 2 Growth Hormone-secreting Neuroendocrine Tumors 3 Diagnosis of Acromegaly 4 Radiological Findings in Acromegaly 5 Clinical Presentation and Findings of Acromegaly 6 Sleep Apnea in Acromegaly 7 Cardiovascular Disorders in Acromegaly 8 Diabetes Mellitus in Acromegaly 9 Arthritis in Acromegaly 10 Malignant Disorders in Acromegaly 11 Mortality in Acromegaly 12 An Overview of the Approach to the Management of Acromegaly 13 Transsphenoidal Surgery in Acromegaly 14 Radiotherapy in Acromegaly 15 Challenging questions in the management of acromegaly in the young 16 Somatostatin Analogues in the Management of Acromegaly 17 Dopamine Agonists in the Management of Acromegaly 18 Growth Hormone Receptor Agonist Therapy in the Management of Acromegaly 19 Combination Medical Therapy in the Management of Acromegaly 20 Long-term Follow-up of Patients with Acromegaly 21 Acromegaly from the Perspective of a Patient