Main description:

The 26th Southern Biomedical Engineering Conference was hosted by the Fischell Department of Bioengineering and the A. James Clark School of Engineering from April 30 - May 2 2010.. The conference program consisted of 168 oral presentations and 21 poster presentations with approximately 250 registered participants of which about half were students. The sessions were designed along topical lines with student papers mixed in randomly with more senior investigators. There was a Student Competition resulting in several Best Paper and Honorable Mention awards. There were 32 technical sessions occurring in 6-7 parallel sessions. This Proceedings is a subset of the papers submitted to the conference. It includes 147 papers organized in topical areas. Many thanks go out to the paper reviewers who significantly improved the clarity of the submitted papers.

Contents:

Traumatic Brain Injury.- Traumatic Brain Injury in Rats Caused by Blast-Induced Hyper-Acceleration.- Early Metabolic and Structural Changes in the Rat Brain Following Trauma in vivo Using MRI.- Principal Components of Brain Deformation in Response to Skull Acceleration: The Roles of Sliding and Tethering between the Brain and Skull.- Investigations into Wave Propagation in Soft Tissue.- Correlating Tissue Response with Anatomical Location of mTBI Using a Human Head Finite Element Model under Simulated Blast Conditions.- Human Surrogate Head Response to Dynamic Overpressure Loading in Protected and Unprotected Conditions.- Blast-Induced Traumatic Brain Injury: Using a Shock Tube to Recreate a Battlefield Injury in the Laboratory.- Wave Propagation in the Human Brain and Skull Imaged in vivo by MR Elastography.- Cavitation as a Possible Traumatic Brain Injury (TBI) Damage Mechanism.- Prognostic Ability of Diffusion Tensor Imaging Parameters among Severely Injured Traumatic Brain Injury Patients.- Auditory Science.- Hair Cell Regeneration in the Mammalian Ear, Is Gene Therapy the Answer?.- Magnetoencephalography and Auditory Neural Representations.- Voice Pitch Processing with Cochlear Implants.- Transcranial Magnetic Stimulation as a Tool for Investigating and Treating Tinnitus.- Bioengineering Education.- A Course Guideline for Biomedical Engineering Modeling and Design for Freshmen.- Classroom Nuclear Magnetic Resonance System.- The Basics of Bioengineering Education.- HealthiManage: An Individualized Prediction Algorithm for Type 2 Diabetes Chronic Disease Control.- Cellular Engineering.- Dynamic Movement and Property Changes in Live Mesangial Cells by Stimuli.- Cooperative Interactions between Myosin II and Cortexillin I Mediated by Actin Filaments during Cellular Deformation.- Devices.- Constitutive Law for Miniaturized Quantitative Microdialysis.- Non-invasive Estimation of Intracranial Pressure by Means of Retinal Venous Pulsatility.- Apparatus for Quantitative Slit-Lamp Ocular Fluorometry.- Changes in Viscoelastic Properties of Latex Condoms Due to Personal Lubricants.- Towards the Objective Evaluation of Hand Disinfection.- Neural Systems Engineering.- In vitro Models for Measuring Charge Storage Capacity.- Discovery of Long-Latency Somatosensory Evoked Potentials as a Marker of Cardiac Arrest Induced Brain Injury.- In vivo Characterization of Epileptic Tissue with Time-Dependent, Diffuse Reflectance Spectroscopy.- Kinematics.- Effects of Initial Grasping Forces, Axes, and Directions on Torque Production during Circular Object Manipulation.- Time Independent Functional Training of Inter-joint Arm Coordination Using the ARMin III Robot.- Kinematic Analysis in Robot Assisted Femur Fracture Reduction: Fuzzy Logic Approach.- Compensation for Weak Hip Abductors in Gait Assisted by a Novel Crutch-Like Device.- Nanotechnology.- Measuring in vivo Effects of Chemotherapy Treatment on Cardiac Capillary Permeability.- Nanoscale "DNA Baskets" for the Delivery of siRNA.- Nanoscale Glutathione Patches Improve Organ Function.- Nanoscale Carnosine Patches Improve Organ Function.- Multiple Lumiphore-Bound Nanoparticles for in vivo Quantification of Localized Oxygen Levels.- Ion-Mobility Characterization of Functionalized and Aggregated Gold Nanoparticles for Drug Delivery.- Implants.- Quantitative Mapping of Vascular Geometry for Implant Sites.- Failure Analysis and Materials Characterization of Hip Implants.- Nano-Wear-Particulates Elicit a Size and Dose Dependent Response by RAW 264.7 Cells.- Viscous Behavior of Different Concentrations of Bovine Calf Serum Used to Lubricate the Micro-textured CoCrMo Alloy Material before and after Wear Testing.- Progressive Wear Damage Analysis on Retrieved UHMWPE Tibial Implants.- Tissue Engineering.- Gum Arabic-Chitosan Composite Biopolymer Scaffolds for Bone Tissue Engineering.- Modification of Hydrogel Scaffolds for the Modulation of Corneal Epithelial Cell Responses.- Making of Functional Tissue Engineered Heart Valve.- Ties That Bind: Evaluation of Collagen I and ?-Chitin.- Chitosan/Poly (?-Caprolactone) Composite Hydrogel for Tissue Engineering Applications.- Disease Modeling.- Modeling and Control of HIV by Computational Intelligence Techniques.- Mathematical Modeling of Ebola Virus Dynamics as a Step towards Rational Vaccine Design.- Respiratory Impedance Values in Adults Are Relatively Insensitive to Mead Model Lung Compliance and Chest Wall Compliance Parameters.- A Systems Biology Model of Alzheimer's Disease Incorporating Spatial-temporal Distribution of Beta Amyloid.- A Mathematical Model of the Primary T Cell Response with Contraction Governed by Adaptive Regulatory T Cells.- A Mathematical Model for Microenvironmental Control of Tumor Growth.- Assessing the Usability of Web-Based Personal Health Records.- Drug Delivery.- Real Time Monitoring of Extracellular Glutamate Release in Rat Ischemia Model Treated by Nimodipine.- Targeted Delivery of Doxorubicin by PLGA Nanoparticles Increases Drug Uptake in Cancer Cell Lines.- Cellular Uptake and Cytotoxicity of a Novel ICG-DOX-PLGA Dual Agent Polymer Nanoparticle Delivery System.- Electrospray - Differential Mobility Analysis (ES-DMA) for Characterization of Heat Induced Antibody Aggregates.- Mechanisms of Poly(amido amine) Dendrimer Transepithelial Transport and Tight Junction Modulation in Caco-2 Cells.- Absorbable Coatings: Structure and Drug Elution.- Special Topics.- A Brief Comparison of Adaptive Noise Cancellation, Wavelet and Cycle-by-Cycle Fourier Series Analysis for Reduction of Motional Artifacts from PPG Signals.- Respiratory Resistance Measurements during Exercise Using the Airflow Perturbation Device.- Comparison of IOS Parameters to aRIC Respiratory System Model Parameters in Normal and COPD Adults.- Effect of Waveform Shape and Duration on Defibrillation Threshold in Rabbit Hearts.- The Measurement and Processing of EEG Signals to Evaluate Fatigue.- Modeling for the Impact of Anesthesia on Neural Activity in the Auditory System.- Cortical Excitability Changes after Repetitive Self-regulated vs. Tracking Movements of the Hand.- What the ENT Wants in the OR: Bioengineering Prospects.- An in vitro Biomechanical Comparison of Human Dermis to a Silicone Biosimulant Material.- Telemetric Epilepsy Monitoring and Seizures Aid.- Spike Detection for Integrated Circuits: Comparative Study.- Effect of Ambient Humidity on the Electrical Conductance of a Titanium Oxide Coating Being Investigated for Potential Use in Biosensors.- Brain Computer Interface in Cerebellar Ataxia.- Biosensors.- Effects of Stray Field Distribution Generated by Magnetic Beads on Giant Magnetoresistance Sensor for Biochip Applications.- Electrostatic Purification of Nucleic Acids for Micro Total Analysis Systems.- Applicability of Surface Enhanced Raman Spectroscopy for Determining the Concentration of Adenine and S-Adenosyl Homocysteine in a Microfluidic System.- Integration of Capillary Ring Resonator Biosensor with PDMS Microfluidics for Label-Free Biosensing.- Surface Plasmon-Coupled Emission from Rhodamine- 6G Aggregates for Ratiometric Detection of Ethanol Vapors.- Formation of Dendritic Silver Substrates by Galvanic Displacement for Surface Enhanced Raman Spectroscopy.- High Specificity Binding of Lectins to Carbohydrate Functionalized Etched Fiber Bragg Grating Optical Sensors.- Oximetry.- Oximetry and Blood Flow in the Retina.- Monitoring and Controlling Oxygen Levels in Microfluidic Devices.- An Imaging Pulse Oximeter Based on a Multi-Aperture Camera.- Fluorescent Microparticles for Sensing Cell Microenvironment Oxygen Levels within 3D Scaffolds.- Determination of in vivo Blood Oxygen Saturation and Blood Volume Fraction Using Diffuse Reflectance Spectroscopy.- Image Analysis.- Fredholm Integral Equations in Biophysical Data Analysis.- High-Resolution Autofluorescence Imaging for Mapping Molecular Processes within the Human Retina.- Local Histograms for Classifying H&E Stained Tissues.- Detecting and Classifying Cancers from Image Data Using Optimal Transportation.- Nanoscale Imaging of Chemical Elements in Biomedicine.- Sparse Representation and Variational Methods in Retinal Image Processing.- Neuromechanics & Rehabilitation.- Optimization and Validation of a Biomechanical Model for Analyzing Running-Specific Prostheses.- Prehension Synergy: Use of Mechanical Advantage during Multi-finger Torque Production on Mechanically Fixed- and Free-Object.- Modeling, Optimizing & Monitoring.- Investigating Vortex Ring Propagation Speed Past Prosthetic Heart Valves: Implications for Assessing Valve Performance.- Transient Heat Transfer in a Dental Prosthesis Implanted in Mandibular Bone.- Characterization of Material Properties of Aorta from Oscillatory Pressure Tests.- Quasi-static Analysis of Electric Field Distributions by Disc Electrodes in a Rabbit Eye Model.- Optimizing the Geometry of Deep Brain Stimulating Electrodes.- Exploratory Parcellation of fMRI Data Based on Finite Mixture Models and Self-annealing Expectation Maximization.- Computational Fluid Dynamic Modeling of the Airflow Perturbation Device.- Biomaterials.- Mechanism and Direct Visualization of Electrodeposition of the Polysaccharide Chitosan.- Chito-Cotton: Chitosan Coated Cotton-Based Scaffold.- Effects of Temperature on the Performance of Footwear Foams: Review of Developments.- A Tissue Equivalent Phantom of the Human Torso for in vivo Biocompatible Communications.- Identification of Bacteria and Sterilization of Crustacean Exoskeleton Used as a Biomaterial.- Neural Stem Cell Differentiation in 2D and 3D Microenvironments.- A Microfluidic Platform for Optical Monitoring of Bacterial Biofilms.- Conduction Properties of Decellularized Nerve Biomaterials.- Reverse Cholesterol Transport (RCT) Modeling with Integrated Software Configurator.- Biomechanics.- Modeling Linear Head Impact and the Effect of Brain-Skull Interface.- Mechanics of CSF Flow through Trabecular Architecture in the Brain.- Impact of Mechanical Loading to Normal and Aneurysmal Cerebral Arteries.- Identification of Material Properties of Human Brain under Large Shear Deformation: Analytical versus Finite Element Approach.- Mechanisms of Traumatic Rupture of the Aorta: Recent Multi-scale Investigations.- Head Impact Response: Pressure Analysis Simulation.- Imaging.- An Introduction to the Next Generation of Radiology in the Web 2.0 World.- Novel Detection Method for Monitoring of Dental Caries Using Single Digital Subtraction Radiography.- Targeted Delivery of Molecular Probes for in vivo Electron Paramagnetic Resonance Imaging.- New Tools for Image-Based Mesh Generation of 3D Imaging Data.- Characterization of Speed and Accuracy of a Nonrigid Registration Accelerator on Pre- and Intraprocedural Images.- Assessment of Kidney Structure and Function Using GRIN Lens Based Laparoscope with Optical Coherence Tomography.- Reliability of Structural Equation Modeling of the Motor Cortex in Resting State Functional MRI.- Quantitative Characterization of Radiofrequency Ablation Lesions in Tissue Using Optical Coherence Tomography.- Clinically Relevant Hand Held Two Lead EEG Device.- A Simple Structural Magnetic Resonance Imaging (MRI) Method for 3D Mapping between Head Skin Tattoos and Brain Landmarks.- Frame Potential Classification Algorithm for Retinal Data.- Raman-AFM Instrumentation and Characterization of SERS Substrates and Carbon Nanotubes.- A Novel Model of Skin Electrical Injury.- Design, Construction, and Evaluation of an Electrical Impedance Myographer.- The Role of Imaging Tools in Biomedical Research: Preclinical Stent Implant Study.- Hard Tissue and Posture.- Optimization of Screw Positioning in Mandible during Bilateral Sagittal Split Osteotomy Using Finite Element Method.- Extraction and Characterization of a Soluble Chicken Bone Collagen.- A Model for Human Postural Regulation.- Development of an Average Chest Shape for Objective Evaluation of the Aesthetic Outcome in the Nuss Procedure Planning Process.- Sickle Cell and Blood Cell.- Sickle Hemoglobin Fiber Growth Rates Revealed by Optical Pattern Generation.- Sickle Cell Occlusion in Microchannels.- Engineering Microfluidics Based Technologies for Rapid Sorting of White Blood Cells.- Peripheral Arterial Tonometry in Assessing Endothelial Dysfunction in Pediatric Sickle Cell Disease.- Comparison of Shear Stress, Residence Time and Lagrangian Estimates of Hemolysis in Different Ventricular Assist Devices.- Cancer.- Drug Resistance always Depends on the Turnover Rate.- Design and Ex Vivo Evaluation of a 3D High Intensity Focused Ultrasound System for Tumor Treatment with Tissue Ablation.- The Dr. James W. Jacobson Symposium on Technologies for Cancer Diagnostics.- Clinical Applications of Multispectral Imaging Flow Cytometry.- Multispectral Imaging, Image Analysis, and Pathology.- Sensitive Characterization of Circulating Tumor Cells for Improving Therapy Selection.- Nanohole Array Sensor Technology: Multiplexed Label-Free Protein Binding Assays.