The Mediterranean diet is characterized by the abundant consumption of olive oil, high consumption of plant foods (fruits, vegetables, pulses, cereals, nuts and seeds); frequent and moderate intake of wine (mainly with meals); moderate consumption of fish, seafood, yogurt, cheese, poultry and eggs; and low consumption of red meat and processed meat products. High consumption of dietary fiber, low glycemic index and glycemic load, anti-inflammatory effects, and antioxidant compounds may act together to produce favorable effects on health status. Collective evidence suggests that Mediterranean diet not only increases longevity by lowering cardiovascular disease, inhibiting cancer growth, but also by protecting the body from age-dependent cognitive decline.Role of the Mediterranean Diet in the Brain and Neurodegenerative Disease provides a comprehensive overview of the effects of all components of Mediterranean diet on the brain as well as their beneficial effects in neurodegenerative diseases. It covers topics on neurodegenerative diseases (Alzheimer disease (AD), Parkinson disease, (PD) Huntington disease (HD), and Amyotrophic Lateral Sclerosis (ALS) and also provides information about how cardiovascular disease, type 2 diabetes, and metabolic syndrome become risk factors for neurodegenerative diseases. This book focuses on how the Mediterranean diet suppresses oxidative stress and neuroinflammation in neurodegenerative diseases as well as signal transduction processes and molecular mechanisms that connect metabolic visceral diseases with neurodegenerative diseases. This book is written for researchers, practitioners, and students in neurology, neuroscience, neuropharmacology, and nutrition.
1. Effect of Mediterranean diet components on neurodegenerative diseases2. The Mediterranean diet and healthy brain aging: Innovations from nutritional cognitive neuroscience3. Molecular and intracellular signaling mechanisms of herbs, spices, and food components in the Mediterranean diet in improving cognitive function4. The molecular bases for protective effect of Mediterranean diet in neurodegenerative disorders5. Multinutrient approach to slow down brain aging and related neurodegenerative disorders6. Effect of Mediterranean diet on healthy brain aging: Involvement of telomerase7. Mediterranean diet and dementia: Can this be a preventive approach?8. Effects of dietary components on microglia inactivation in Alzheimer's disease9. Contribution of Mediterranean diet in the prevention of Alzheimer's disease10. Mediterranean diet and its impact on cognitive functions in aging11. Mediterranean diet and diabetic retinopathy12. Mediterranean diet as a potential strategy to reduce cognitive decline and dementia in elderly13. Effect of Mediterranean diet components on type 2 diabetes and metabolic syndrome14. Interactions between age, diet and insulin, and their effect on cognition: Implications for Alzheimer's Disease15. The use of polyphenols for the treatment of Alzheimer's disease16. Neuroprotective effects of garlic in model systems of neurodegenerative diseases 17. Neuroprotective properties of wine: Implications for the prevention of cognitive impairment18. Red wine retards AB deposition and neuroinflammation in Alzheimer's Disease19. Contribution of diabetes and metabolic syndrome in the pathogenesis of Alzheimer disease20. Effects of western, Mediterranean, vegetarian, and Okinawan diet pattern on human brain21. Mediterranean diet is beneficial: But, how and why?22. Multi-nutrient intervention in the prevention and treatment of dementia23. Cardioprotective properties of wine: Implications for the management of neurodegenerative diseases24. Anti-inflammatory properties of dietary n-3 polyunsaturated fatty acids protect against cognitive decline in aging and neurodegenerative diseases25. Effects of dietary omega-3 fatty acid consumption26. Interplay between lipid mediators and immune system in the promotion of brain self-repair27. Importance of fruit and vegetable-derived flavonoids in the Mediterranean diet: Molecular and pathological aspects28. Perspective and directions for future research