Main description:

Vaccines have historically been considered to be the most cost-effective method for preventing communicable diseases. It was a vaccine that en abled global eradication of the dreaded disease smallpo. .

Contents:

I Opening Remarks.- 1. Vaccinology: The Two Revolutions.- II Public Health Perspective-The Present Scene.- 2. Vaccinology and the Goal of Health for All.- 3. Toward Universal Immunization: 1990.- 4. New and Improved Techniques for Vaccine Production.- 5. Transfer of Vaccine Production to the Developing World: Rabies Vaccine.- 6. Policy for Developing Countries for Storage, Distribution, and Use of Essential Vaccines for Immunoprophylaxis.- III Environmental Factors Modulating The Efficacy of The Vaccine.- 7. Immunity in Tuberculosis: Environmental Versus Intrinsic Factors Modulating the Immune Responsiveness to Mycobacteria.- 8. Geographic Variation in Vaccine Efficacy: The Polio Experience.- IV Hepatitis.- 9. Molecular Immunology of Viral Antigens in Hepatitis B Vaccinations.- 10. Biologic Significance of Pre-S Antigen and Anti-Pre-S Antibodies in Hepatitis B Virus Infection.- 11. Enterically Transmitted Hepatitis Viruses: Prospects for Control.- 12. Immunological Characterization of a Viral Agent Involved in Epidemic and Sporadic Non-A Non-B Hepatitis.- V Gastrointestinal Infections.- 13. Attenuated Oral Typhoid Vaccine Ty 21a.- 14. Oral B Subunit-Whole Cell Vaccine Against Cholera: From Basic Research to Successful Field Trial.- 15. Prospects of Immunization Against Cholera by Adhesive Antigen.- 16. Protective Antigens of Vibrio cholerae.- 17. Rationale for the Development of a Rotavirus Vaccine for Infants and Young Children.- 18. Mucosal Immunity in the Gastrointestinal Tract in Relation to ETEC Vaccine Development.- 19. Shigella Vaccines.- 20. DNA Sequence Homology Among Genes of Shigella spp. and Enteroinvasive Escherichia coli...- 21. Mucosal and Acquired Immunity in Giardiasis and Its Relation to Diarrhea and Malabsorption.- 22. Immunology of Entamoeba histolytica in Human and Experimental Hosts.- 23. Molecular Comparisons Among Entamoeba histolytica Strains Using DNA and Protein Profiles.- VI Filariasis.- 24. Importance of Antibody Class in Helminth Infections.- 25. Immunodiagnosis of Filariasis.- VII Veterinary Vaccines.- 26. Development, Production, and Application of Vaccines in Foot-and-Mouth Disease Control in India.- 27. Cell Culture Vaccine Against Bovine Tropical Theileriosis.- VIII Leprosy.- 28. Present Approaches to Immunotherapy and Immunoprophylaxis for Leprosy.- 29. Armadillo-Derived Killed M. leprae: Candidate Vaccine Against Leprosy.- 30. Mycobacterium w: Candidate Vaccine Against Leprosy with Antigens Cross-Reactive with Three Major Protein Antigens of Mycobacterium leprae.- 31. Molecular Approaches to Developing a Vaccine for Leprosy,.- 32. Immunodiagnosis of Leprosy.- 33. Immunodiagnostic Approaches to the Detection of M. leprae Infection in Leprosy.- 34. Serological Survey of Leprosy Using a Monoclonal Antibody-Based Immunoassay and Phenolic Glycolipid ELISA.- IX Malaria and Leishmaniasis.- 35. Antisporozoite Malaria Vaccine Development Based on Circumsporozoite Protein.- 36. Malaria Sporozoite Vaccine Development: Recent Progress.- 37. Community-Based Integrated Vector Control of Malaria in India.- 38. Leishmaniasis and Malaria: New Tools for Epidemiological Analysis.- X New Approaches to Vaccinology.- 39. Vaccinia Virus Expression Vectors.- 40. Vaccinia Recombinants Expressing Foreign Antigens: Antiviral and Antitumor Immunity.- 41. Liposomes as Carriers of Vaccines.- 42. A Short Primer on Vaccine Design: Focus on the Interrelatedness of Antigenic Determinants Addressing Various Lymphocyte Sub-populations.- 43. Next Steps in the Evolution of Vaccinology.