Main description:

Neurological Complications of Systematic Cancer and Antineoplastic Therapy provides an in-depth review of common manifestations related to neurology that occur in patients with systemic cancer. These include brain metastases, spinal cord compression, cerebrovascular events, and leptomeningeal disease. The book also discusses less common complications such as paraneoplastic disorders and neoplastic plexopathy.

Highlights include:

The pathophysiology and molecular biology of cancer and the metastatic phenotype
Metastatic spread to cranial and peripheral nerves and brachial and lumbosacral plexuses
Metabolic and nutritional disorders
CNS infections
Neurological complications of immunotherapy and bone marrow transplants

Additional chapters review problems related to each specific tumor type, such as breast, lung, and colorectal, as well as gynecological cancer, genitourinary cancer, and malignant melanoma. The book also discusses neurological complications related to treatments such as radiation and chemotherapy.

Bringing clinical trial knowledge from the bench to the bedside, this volume is an essential reference for the practicing oncologist and neurologist.

Contents:

METASTATIC NEUROLOGICAL COMPLICATIONS. Pathophysiology of CNS/PNS Mets. Intracranial Metastases. Spinal Mets & ESCC. Leptomeningeal Mets. Mets to Cranial/Peripheral N. Mets to Brachial & L/S Plexus. NON-METASTATIC NEUROLOGICAL COMPLICATIONS. Cerebrovascular Disorders. Metabolic/Nutritional Disorders. CNS Infections. Paraneoplastic Syndromes. NEUROLOGICAL COMPLICATIONS OF SPECIFIC NEOPLASMS. Neuro Comps of Lung Cancer. Neuro Comps of Breast Cancer. Neuro Comps of Melanoma. Neuro Comps of Leuk/Lymph. Neuro Comps of Head/Neck CA. Neuro Comps of Gynecol CA. Neuro Comps of GI CA. Neuro Comps of GU CA. Neuro Comps of Sarcomas. Neuro Comps of Myeloma. Neuro Comps of Pediatric CA. NEUROLOGICAL COMPLICATIONS OF ANTINEOPLASTIC THERAPY. Neuro Comps of Radiotherapy. Neuro Comps of Chemotherapy. Neuro Comps of Immuno Tx. Neuro Comps of BMT. Neuro Comps of Steroids/Supp Tx. PSYCHIATRIC, PAIN, AND PSYCHOSOCIAL ISSUES AND SUPPORTIVE CARE ISSUES. Psychiatric Issues. Pain Syndromes & Tx. Psychosocial Issues. Supportive Care.