Main description:

The Eleventh International Latin American Symposium is an important mile stone reflecting the rapid development of basic biochemistry in Latin America. The topic "Gene Expression and Its Regulation" was received enthusiastically, and, thanks to the vision of our Argentine colleagues, the program developed rapidly under the leadership of Dr. Gabriel Favelukes as General Secretary of the Symposium. It is interesting to note the tremendous progress that has been made in basic and applied sciences in Latin America over the past few years. The increasing initiative and leadership being demonstrated by our Latin American colleagues in organizing these symposia is a most satisfying development that speaks well for the future of science in Latin America. The early publication of this symposium has been made possible through the efforts of an editorial board consisting of Dr. F. T. Kenney (Oak Ridge National Laboratory), Dr. Gabriel Favelukes (University of La Plata), Dr. Barbara Ham kalo (Oak Ridge National Laboratory), and Dr. J. T. August (Albert Einstein College of Medicine). As in previous symposia, excellent support has come from the Ford Founda tion through a grant to the National Academy of Sciences, the United States Atomic Energy Commission, the National Science Foundation, OAS, and other groups. Through the cooperation of the authorities at the University of La Plata, the Albert Einstein College of Medicine (the United States cosponsoring university), and other schools, this very successful symposium was made possible.

Contents:

1. What Do We Know About Protein Synthesis?.- 2. Structure and Function of Phage RNA: A Summary of Current Knowledge.- 3. Host Proteins in the Replication of Bacteriophage RNA.- 4. On the Regulation of RNA Synthesis in Escherichia coli.- 5. Interconvertible Forms of Bacterial RNA Polymerase.- 6. Visualization of Genetic Transcription.- 7. Structural and Functional Studies on Mammalian Nuclear DNA-Dependent RNA Polymerases.- 8. Regulation of Nucleolar DNA-Dependent RNA Polymerase by Amino Acids in Ehrlich Ascites Tumor Cells.- 9. Rhynchosciara angelae Salivary Gland DNA: Kinetic Complexity and Transcription of Repetitive Sequences.- 10. Hormonal Regulation of Ovalbumin Synthesis in Chick Oviduct.- 11. mRNA Synthesis in Erythropoiesis: Specific Effect of Erythropoietin on the Synthesis of DNA-like RNA.- 12. Messenger RNA: Its Origin and Fate in Mammalian Cells.- 13. Messenger RNA Processing in Vertebrate Cells.- 14. Effects of Neonatal Thyroidectomy on Nuclear and Microsomal RNA Synthesis in Developing Rat Brain.- 15. Structure-Function Relations in tRNA.- 16. Nucleotide Sequence and Function of Transfer RNA and Precursor Transfer RNA.- 17. Changes in Specificity of Suppression in Transfer Ribonucleic Acid Mutants.- 18. Conformational States of Transfer Ribonucleic Acids.- 19. Modification of Leucine tRNA of Escherichia coli After Bacteriophage T4 Infection.- 20. Reconstitution of 50S Ribosomal Subunits and the Role of 5S RNA.- 21. Electron Microscopic Studies of Escherichia coli Ribosomal Subunits.- 22. Aggregation Properties of Rat Liver Ribosomes.- 23. Studies on Hela Cell Nucleoli.- 24. On the Movement of the Ribosome Along the Messenger Ribonucleic Acid and on Apparent Changes in Ribosome Configuration During Protein Synthesis.- 25. Initiation of DNA Synthesis by Oligoribonucleotides.- 26. "Enzymatic" and "Nonenzymatic" Translation.- 27. The Ribosome Cycle in Bacteria.- 28. Antibiotic Action in Protein Synthesis.- 29. Mechanisms of Mammalian Protein Synthesis.- 30. The Effect of Sodium Fluoride, Edeine, and Cycloheximide on Peptide Synthesis with Reticulocyte Ribosomes.- 31. Intermediate Stages in the Ribosomal Cycle of Reticulocytes.- 32. Studies on the Binding of Aminoacyl-tRNA to Wheat Ribosomes.- 33. Polymerization Factors in Yeast.- 34. Modifications of Polysome-Associated RNA After Poliovirus Infection.- 35. On the Relationship Between Transcription, Translation, and Ribosomal RNA Synthesis During Microsomal Hydroxylase Induction.- 36. Ribosomes in Reticulocyte Maturation.- 37. Hormonal Mechanisms in Regulation of Gene Expression.- 38. Synthesis of Mitochondrial Proteins.- 39. Stimulation of the Synthesis of Inner Mitochondrial Membrane Proteins in Rat Liver by Cuprizone.- 40. Hormonal Effects on Mitochondrial Protein Synthesis.