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MORE ABOUT THIS BOOK
Main description:
The molecular mechanisms and protein species involved in enamel development and mineralization are areas of active research and debate. There is much to learn about the roles of the enamel matrix proteins (e.g. amelogenins and enamelins/tuftelins and ameloblastins) secreted by ameloblasts, as well as the process of abnormal enamel development, which may result either from inherited genetic defects (amelogenesis imperfecta) or from systemic or environmental factors such as fluoride. The aim of this book is to evaluate many of the recent advances in this field: the genetics and structural biology of the enamel matrix proteins; the structure/function relationships of these proteins in normal and diseased enamel; the new cellular, molecular, evolutionary and computational approaches that are fuelling progress towards the understanding of enamel genesis; and the biomimetic or tissue engineering approaches that may result in improved diagnostics and therapeutics. It contains lively debates from an international group of experts who have identified future directions both for the ?science? of dental enamel and health–related opportunities.
Back cover:
The molecular mechanisms and protein species involved in enamel development and mineralization are areas of active research and debate. There is much to learn about the roles of the enamel matrix proteins (e.g. amelogenins and enamelins/tuftelins and ameloblastins) secreted by ameloblasts, as well as the process of abnormal enamel development, which may result either from inherited genetic defects (amelogenesis imperfecta) or from systemic or environmental factors such as fluoride. The aim of this book is to evaluate many of the recent advances in this field: the genetics and structural biology of the enamel matrix proteins; the structure/function relationships of these proteins in normal and diseased enamel; the new cellular, molecular, evolutionary and computational approaches that are fuelling progress towards the understanding of enamel genesis; and the biomimetic or tissue engineering approaches that may result in improved diagnostics and therapeutics. It contains lively debates from an international group of experts who have identified future directions both for the ?science? of dental enamel and health–related opportunities.
Contents:
Partial table of contents:
Tooth Morphogenesis and the Differentiation of Ameloblasts (I. Thesleff, T. Åberg).
Microstructure of Enamel (A. Boyde).
Structure, Crystal Chemistry and Density of Enamel Apatites (J. Elliott).
Inherited Enamel Defects (B. Bäckman).
Molecular Biology of Hereditary Enamel Defects (M. Aldred P. Crawford).
Determinants and Mechanisms of Enamel Fluorosis (G. Whitford).
Indexes.
PRODUCT DETAILS
Publisher: John Wiley & Sons Ltd (Wiley–Blackwell)
Publication date: September, 2007
Pages: 284
Dimensions: 155.00 x 236.00 x 20.00
Weight: 600g
Availability: Not available (reason unspecified)
Subcategories: Diseases and Disorders
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CUSTOMER REVIEWS
"...must represent an essential read...for...those teaching the subject to undergraduates...also those with an active research interest in the area." ( Biochemical Education, Vol. 26, 1998)