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Biological Modulation of Solid Tumours by Interferons
Series: ESO Monographs
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Main description:

In the 1960s, it was reported that interferons have antitumour activity in different experimental models. Since that time, numerous studies have been performed to elucidate the various mechanisms of action that have been proposed. However, there is much controversy in the literature and promising preclinical findings failed to translate into substantial clinical progress. The present book gives a critical overview of current knowledge of how interferons act in solid tumours. For this purpose, after two chapters of general aspects of interferon action and interaction, selected solid tumours which are commonly considered difficult to treat in advanced stages are discussed with respect to both preclinical data and clinical experience.


Contents:

The Interferons: Basic Concepts Concerning their Modulatory Effects on the Immunological System.- Biomodulation of 5-Fluorouracil by Interferon-Alpha.- Malignant Melanoma.- Head and Neck Cancer.- Breast Cancer.- Renal Cell Carcinoma.- Prostate Cancer.


PRODUCT DETAILS

ISBN-13: 9783642788680
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: December, 2011
Pages: 82
Weight: 238g
Availability: Available
Subcategories: Immunology, Oncology
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