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Amyloid and Amyloidosis 1990
VIth International Symposium on Amyloidosis August 5-8, 1990, Oslo, Norway
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Both scientifically and socially the Vlth International Symposium on Amyloidosis, August 5 - 8, 1990 in Oslo was a great success. There were three and a half intensive days. It started with the Opening Ceremony, particularly highlighted with the Norway-Norway multi media show by David Cochron, and ended with a visit to the Edvard Munch museuro and the Farewell Salmon Dinner on the evening of August 8 (not to forget the "happy birthday" song for Dorothea Zucker-Franklin at the breakfast table the following morning). In between was the intellectual penetration into the science of amyloidosis and amyloid proteins, and a deepening of many friendships among young and old "amyloidologists", together with some of the cultural and historical features of Oslo and Norway. Among the numerous Ietters of thanks and gratitude that we have received, the senior organizer of the previous meeting, Takashi lsobe said it briefly and eloquently: "You have overwhelmed us, you have performed a drama with joy and cheer, you have hosted so nicely with lovely secretariat, you have arranged impressive hospitality in every respect, you certainly did for all of us" Now we are left with the proceedings book for the three coming years until the next symposium in Kingston, Canada, which will be organized by Drs. Robert Kisilevsky and Thomas Muckle from the Department of Pathology at Queens University in 1993. The scientific contributions herein cover all the sessions of the meeting.


Contents:

Welcome.- Elliott F. Osserman In Memoriam.- The 1990 Guidelines for Nomenclature and Classification of Amyloid and Amyloidosis.- I Protein Aa/Saa and Secondary Amyloidosis.- The Human Saa Genes and Their Regulation by Cytokines.- Genetic Isofocusing Variant of Human Serum Amyloid A.- Sequence Analysis of a Third Human Saa Gene.- Human Serum Amyloid-A Protein: Variability Demonstrated by Cdna Sequencing and Expression Studies.- Abyssinian Cat Model of Aa Amyloidosis: Saa Gene Analysis.- Mink Serum Amyloid a Protein - Expression and Primary Structure of Amyloidogenic and Non-Amyloidogenic Isotypes.- Primary Structure of Two Rabbit Serum Amyloid a Proteins (Saa) Based on Cdna Sequence.- Biosynthesis and Processing of Saa by Mouse L-Cells Transfected with the Human Saag9 Gene.- Regulation of Serum Amyloid a (Saa) Synthesis in Hep 3B Cells by Cytokines and Corticosteroids.- Regulation of Saa Synthesis by Cytokines in a Human Hepatoma Cell Line.- Saa Secretion from Cytokine-Stimulated Human Hepatoma Cells Requires Hdl.- Interferon a Induces Tnf Elevations in Vivo. Correlation with Other Acute Phase React Ants.- Acute Phase Protein, Serum Amyloid a, Inhibits Il-1- and Tnf-Induced Fever and Hypothalamic Pge2 In Mice.- Human Recombinant TNF-? and Poly I. Poly C Induce Saa and Enhance Amyloidosis in Hamster.- The Physiology of the Acute Phase Serum Amyloid a (Saa) Response in Mice.- Mouse Saa3: Detection in Mouse Tissues with Specific Antibody.- Generation and Use of Site-Specific Antibodies Against Saa.- The N-Terminus is the Lipid-Binding Site of Saa: Supporting Evidence by Moabs.- Epitope Mapping of Amyloid-a Protein Using Monoclonal Antibodies.- Reactive (Aa) Amyloidosis in a 14 Year Old with No Predisposing Disease.- Induction of Amyloidosis in Mice: Preparation of Active Azocasein (Azo) and Effect of Endotoxin (Lps).- Serum Amyloid a (SAA) Induction in the Serum High Density Lipoproteins of the Syrian Hamster.- The Complete Primary Structure of Bovine Serum Amyloid Protein a (SAA) and of Tissue Amyloid Fibril Protein a (AA) Subspecies.- Degradation of Saa in Amyloid Fibrils by Elastase.- Evolutionary Aspects of Protein Saa.- Strain Specific Variation in Expression of Novel Mouse Apo-Saa Isoforms.- Saa Isotypes in Patients with Secondary Amyloidosis.- Differential Regulation of Human Serum Amyloid a Isoforms.- The Effect of SAA-Derived Fragment - SAA2-82 - On Platelet Aggregation.- Serum Amyloid a, An Acute Phase Protein, Inhibits Platelet Activation.- Serum Amyloid a (SAA)-Related Peptide Isolated from Synovial Fluid Modulates Superoxide Production by Human Neutrophils.- Antiplatelet Aggregation Activity of Serum Amyloid a (SAA) Related Peptides.- Effect of Purified Serum Amyloid a on Growth and Differentiation of Transformed Cells.- II Al Protein and Light Chain Related Amyloidosis.- Primary Systemic Amyloidosis (AL) In 1990.- Comparison of the Amino Acid Sequences of Ten Kappa I Amyloid Proteins for Amyloidogenic Sequences.- Characterization of a X Al Protein and Two Amyloidgenic X Bjp in Three Cases of Immunoglobulin Amyloidosis.- Biclonality in Amyloidosis Patient Mal: One Clone Producing an Amyloidogenic, the Other a Non-Amyloidogenic Kappa L-Chain.- Complete Amino-Acid Sequence of a Kappa Light Chain Fragment Isolated from the Urine of Amyloidosis Patient Mal.- Comparative Studies of Two al Chains of Kappa-III Light Chain Origin with and Without Attached Carbohydrate (Al So124 and Al 700).- Structural Studies of two Carbohydrate-Containing Al Chains (?II) Al NoV and Al Mc.- Complete Amino-Acid Sequence of Al-Bence-Jones Protein Pol of the Lambda I Subclass.- Complete Amino-Acid Sequence of Al-Lambda 1.1 Bence-Jones Protein Ezi.- Complete Amino Acid Sequence of A A Amyloid Fibril Protein Isolated from the Liver of Amyloidosis Patient Dia.- Systemic Al Amyloidosis In A Cat.- Experimental Production of Human Amyloidosis Al.- Al Amyloid, L-Chain and L&H-Chain Deposition Diseases: Comparison of Ig Synthesis and Tissue Deposition.- Gene Rearrangement Studies in the Diagnosis of 'Primary' Systemic Amyloidosis and Nodular Localized Cutaneous Amyloidosis.- Clinicopathologic Correlations in 109 Patients with Systemic Amyloidosis Studied by Immunocytochemistry.- Quantification of Non-Light Chain Amyloid Precursors and Acute Phase-Related Proteins in Al-Amyloid Sera.- Incidence and Epidemiology of Primary Systemic Amyloidosis (AL) in Olmsted County, Minnesota: 1950 Through 1989.- Low Incidence of Al Amyloidosis in Japan.- Clinical Indications of Systemic Amyloidosis in Myeloma Patients.- Bence Jones Proteinemia Without Bence Jones Proteinuria in Al Amyloidosis.- Systemic Amyloidosis and Monoclonal Gammopathy in Three Italian Siblings: a Familian Case of Al-Amyloidosis?.- Primary Systemic Amyloidosis (Al): a Randomized Trial of Colchicine Vs. Melphalan And Prednisone Vs. Melphalan, Prednisone, and Colchicine.- Response Rates and Survival in Primary Systemic Amyloidosis.- Urinary Protein Patterns Predict Survival in Primary Systemic Amyloidosis (Al).- ss2-Microglobulin Predicts Survival in Primary Systemic Amyloidosis (AL).- Cutaneous Amyloidosis in a Horse. Partial Amino Acid Sequence Analysis of an Equine Immunoglobulin-Lambda Light Chain.- Experimental Amyloid Casts in Mice Induced by Injection of a Human Bence Jones Protein.- III Amyloid Enhancing Factor (AEF), Amyloid P-Component and Proteoglycans in Amyloidosis.- Common Elements in Amyloidosis.- Metabolic Studies of Radioiodinated Serum Amyloid P Component in Normal Subjects and Patients with Systemic Amyloidosis.- Structural and Functional Studies of Serum Amyloid P Component.- Quantification of Amyloid P-Component in Multiple Tissues of Patients with Primary and Familial Amyloidosis.- A Primed State Exists in Vivo Following Regression of Murine AA Amyloidosis.- Serum Amyloid P-Component (SAP) Regulation by Sex-Steroids in Rats: Compared with C-Reactive Protein (CRP).- Acute Phase Protein Response to Collagen Induced Arthritis in Mice.- An Attempt to Study the Role of Serum Amyloid P Component in the Formation of Amyloid Deposits in a Transgenic Mouse Model of Familial Amyloidotic Polyneuropathy.- Differential Regulation of Sap Gene Expression in Syrian and Armenian Hamsters.- Isolation of cDNA Clones and Expression Analyses for Rat Serum Amyloid P (SAP) Component.- Isolation of a 16 KD Fraction with Extremely High AEF Activity.- Amyloid Enhancing Factor (AEF) - Induced Amyloidosis Lacks Inflammatory Reaction.- The Tissue Origin of Amyloid Enhancing Factor Determines its Ability to Induce SAA Gene Expression.- Pmsf-Sensitive Serine Esterase-Activity and Fibril-Derived Amyloid Enhancing Factor (FAEF)-Activity in Hamster are Not Related.- Induction of Amyloid Deposition by Subfractions of the Amyloid Enhancing Factor Extracted from Brain of Patients with Alzheimer's Disease.- Isolation of Amyloid Enhancing Factor (AEF).- Effects of Amyloid Enhancing Factor on in Vitro Kupffer Cells.- Macromolecular Characteristics of AA Type Amyloid Associated Polysaccharides from Human Liver, Kidney and Spleen with AA Amyloid Secondary to Rheumatic Disease.- Heparan Sulfate Accumulation in the ss-Amyloid Protein Containing Lesions of Down's Syndrome Occurs Prior to the Appearance of Fibrillar Amyloid.- Rapid Synthesis of cRNA Probes for SAA, SAP and Heparan Sulfate Proteoglycan Mrnas by Transcription of Polymerase Chain Reaction Generated Templates.- Basement Membrane Components in Addition to HSPG are Present in Murine AA Amyloid Deposits.- The Basement Membrane form of Heparan Sulphate Proteoglycan is Part of Human IAPP Amyloid Deposits in the Islets of Langerhans.- Isolation and Characterisation of the Integral Glycosaminoglycan Constituents of Human AA And Al Amyloid Fibrils.- Basement Membrane Components and Protein AA in Renal Amyloid Deposits.- High Molecular Weight Polysaccharides in Familial Cardiac Amyloid of Danish Origin Related to Transthyretin Met 111.- IV Cystatin C, ss-2 Microglobulin, APO AI and APO All Related Amyloidoses.- Point Mutation in Autosomal Dominant forms of Amyloidosis.- Perturbation of Processing of Cystatin C in Monocytes from Patients with Hereditary Cystatin C Amyloid Angiopathy.- Molecular Biology of Hereditary Cystatin C Amyloid Angiopathy in Iceland.- Cerebral Amyloid Angiopathy Associated with Cerebral Hemorrhage with the Deposition of Cystatin C: Study on Japanese Cases.- Several ss2-Microglobulin Fragments Identified in An Amyloidoma in A Patient with Long-Term Hemodialysis.- Clinical Evaluation of Osteoarthropathy in 43 Patients on Hemodialysis, Using Cuprophane Membranes for ? 5 Years.- ss2-Microglobulin-Derived Amyloid and Calcium in Long-Term Dialysis Patients.- In Vivo Metabolism of A Mutant Apolipoprotein A-I (Arg-26) Associated with Hereditary Amyloidosis.- New Usa Family Has Apolipoprotein A1 (ARG26) Variant.- Molecular Genetic Study of Mouse Senile Amyloidosis.- Fluorometric Examination of Tissue Amyloid Fibrils in Murine Senile Amyloidosis: Use of the Fluorescent Indicator, Thioflavine T.- The Low Leukocyte (LLC) Mouse, A Second Model of "Senescence Accelerated" Amyloidosis Associated with Apolipoprotein All Pro5 ? Gln; Prevalence of this Substitution Among Inbred Strains of Mice.- Age-Related Amyloid in the Aorta.- Complete Primary Structure of Amyloid Protein in Finnish Hereditary Amyloidosis. Identification of a New Type of Amyloid Protein Derived from Variant (Asn-187) Gelsolin.- Polymerization of Gelsolin Variant Fragment in Tissue Causes Familial Amyloidosis, Finnish Type (FAF).- Gelsolin-Related Amyloidosis. Immunohistochemical Studies in Finnish Hereditary Amyloidosis with Antibodies to a Synthetic Dodecapeptide of the Amyloidogenetic Region of Gelsolin.- Familial Amyloidosis, Finnish Type.- Shared Gelsolin Antigenicity Between Familial Amyloidosis Finnish Type (FAF) and One form of Familial Lattice Corneal Dystrophy (LCD) with Polyneuropathy from the United States.- V Amyloid Proteins Related to Polypeptide Hormones.- Polypeptide Hormones and Amyloid.- Islet Amyloid Polypeptide (IAPP): Structure of its cDNA and Gene and the Identification of Species Differences of Importance for Islet Amyloid Formation.- Human Islet Amyloid Polypeptide (IAPP): Identification in Human Pancreas, Establishment of Radioimmunoassay, and its Response to Physiological Stimulation.- Rat Islet Amyloid Polypeptide (IAPP): Isolation and Sequence Determination, Immunohistochemical Study, and its Secretion from Pancreas.- Factors Affecting Diabetogenesis and Amyloidogenesis are Provided by Studies of IAPP in the Dog and Cat.- Islet Amyloid Polypeptide: Synthetic Peptides for Study of the Pathogenesis of Islet Amyloid.- Intracellular Formation of Amyloid Fibrils in B-Cells of Human Insulinoma and Pre-Diabetic Monkey Islets.- A Comparative Study Between Human B-Cell Insulin and Islet Amyloid Polypeptide (IAPP) Storage and Amyloid Deposition in Type 2 Diabetes Mellitus And in Non-Diabetics.- Pancreatic Islet Amyloid in the Degu is Derived from Insulin.- Isolated Atrial Amyloid Deposits. Immunochemical Evidence for the Presence of Polypeptides with Molecular Weights Higher and Lower Than Atrial Natriuretic Peptide (ANP).- Raised Prevalence of Isolated Atrial Amyloidosis in Chronic Heart Disease.- Isolated Atrial Amyloidosis. Increased Frequency in Patients with Congestive Cardiac Failure.- Characterization of Molecular forms of Calcitonin in Amyloid Fibrils from Medullary Carcinoma of the Thyroid.- VI Patho-Fibrillogenesis and Amyloid Proteins.- Pathofibrillogenesis and Amyloid Proteins.- The Sulphate and Chloride Ions have Different Effects on the Structure of AA Amyloid Fibrils.- Kinetic Properties of Amyloid Fibril Polymerization in Vitro.- In Vitro Assembly of Murine Amyloid a Protein, Two Murine Serum Amyloid a Proteins, and Normal Human Transthyretin to form Amyloid-Like Fibrils.- Secondary Structure Changes in Mutant Transthyretins After Proteolysis by Neutrophilic Serine Proteases.- Production of Amyloidogenetic Peptides from Human Immunoglobulin Light (L)-Chains.- Predominance of One SAA Isotype (SAAI) in Human Reactive Amyloid.- A Histochemical Model of the Amyloid Fibril.- High Molecular Weight Proteins, Sensitive to Collagenase Digestion are Intimate Constituents of Amyloid Deposits.- Intraperitoneal Amyloid Formation by Amyloid Enhancing Factor Rich Macrophages in Ascitic Fluid.- Histochemically Recognizable Changes of Amyloid Fibrillogenic Macrophages.- Ultrastructural Aspects of Cell Membrane in AA-Amyloidogenesis.- Amyloid Fibril Formation in the Rough Endoplasmic Reticulum of Plasma Cells from a Patient with Localized A? Amyloidosis.- A Comparative Study of Amyloid Formation and Resorption Using Immunoelectron Microscopy.- A Histochemical, Immunohistochemical, Ultrastructural and Immunoelectron Microscopical Characterization of Cerebrovascular Amyloid and Diffuse Plaques in Autopsied Aged Dogs.- Increased Binding of Acute Phase Lipoproteins by Peritoneal Macrophages (MOS) in Mice.- Characterization of Non-AA Proteins in Amyloid Fibrils Obtained from a Cow With Chronic Infection.- Compositional Analyses of Amyloid Fibrils.- Intratumour Amyloidosis in Primary and Metastatic Nasopharyngeal Carcinoma: an Immunohistochemical and Ultrastructural Study.- Intratumour Amyloidosis in Carcinoma of the Cervix.- VII Transthyretin Related Amyloid and Hereditary Amyloidosis.- Molecular Biology of Amyloidogenesis in the Transthyretin Related Amyloidosis.- Studies on the Molecular Arrangement in Transthyretin-Related Familial Amyloidotic Polyneuropathy Fibrils.- X-Ray Crystal Structure of the Met-30 Variant of Human Prealbumin (Transthyretin).- Disulfide Bond Formation of Transthyretin (TTR) As Possible Initial Step of Familial Amyloid Polyneuropathy (FAP).- Structure of Transthyretin Molecules in Amyloid Fibrills from the Vitreous Body in Individuals with the Met30 Mutation.- Formation of Fibrils by Normal Transthyretin and Synthetic Transthyretin Fragments In Vitro.- First Turkish Family with FAP has Homozygous Met 30 Ttr.- A New Transthyretin Variant Associated with Familial Amyloidotic Polyneuropathy in an Italian Kindred.- Clinical Characterization of a New TTR Variant in an Italian Family: TTR Ala 49.- A TTR Acidic Variant Dna Analysis of Homozygous and Heterozygous Individuals.- Asn 90 is the Variant TTR in An Italian Fap Kinship.- Frequency of the Position 122 (Val?Ile) Variant Transthyretin Gene in Blacks without Amyloidosis.- Variant Transthyretins in Familial Amyloidotic Polyneuropathy (FAP).- Three Novel Variants of Transthyretin Identified in Three Japanese Kindreds with Familial Amyloidotic Polyneuropathy.- A Possible New Transthyretin Genetic Variant in a Family with Cardiac Amyloidosis.- Structural Studies of Transthyretin and Related Fragments Obtained from a Swedish Patient (V-AS 280) with Senile Systemic Amyloidosis.- The Transthyretin cDNA Sequence is Normal in Transthyretin-Derived Senile Systemic Amyloidosis.- A Recombinant System for Production of Variant Type Human Transthyretin(TTR).- Assessement of Structure and Binding Capacities of Secreted Mutant Transthyretins by an E.Coli System.- Structure and Function of Recombinant Human Transthyretin.- Detection of Variant Transthyretin Genes by Restriction Analysis of PCR-Amplified Genomic Dna.- Myelin P2 Protein in Transthyretin (Ser-84) Vitreous Amyloid.- Cloning and Trimming of the TTR-Cdna Gene by PCR.- Pathological Similarity of Transgenic Mice Carrying the Human Mutant Transthyretin Gene to Human Familial Amyloidotic Polyneuropathy (FAP) Type I.- Prealbumin Type Cerebral Amyloid Angiopathy in Familial Amyloid Polyneuropathy.- Amyloid Localized to the Tenosynovium at Carpal Tunnel Release: Immunohistochemical Identification of Amyloid Type.- Reevaluation of 134 Patients with Familial Amyloidotic Polyneuropathy (FAP) in Japan, Kumamoto Focus.- Sympathetic Skin Response in Familial Amyloid Polyneuropathy.- Extrinsic and Intrinsic Nerve Lesions of the Intestine in Type I Familial Amyloid Polyneuropathy.- Sex Differences and Age-Dependent Penetrance in Fap-Type I.- Parental Transmission and Age-of-Onset in Familial Amyloidotic Polineuropathy (Portuguese Type).- Anticipation of Age-of-Onset in Familial Amyloidotic Polineuropathy (Portuguese Type).- Sporadic, Late-Onset Case of Familial Amyloid Polyneuropathy Type I (Andrade) - A Clinicopathological Study.- Familial Amyloidosis without Transthyretin (TTR) Involvement: an Unusual Presentation.- VIII Amyloid in Alzheimer's Disease.- Mechanisms of Amyloid Fibril Formation in Alzheimer's Disease and Other Dementias.- Amyloid ss-Protein Deposition as a Seminal Pathogenetic Event in Alzheimer's Disease.- Proteolytic Processing of ss-Amyloid Protein-Related Synthetic Peptides and the ss-Protein Precursor by a Protease Purified from Alzheimer's Disease Brain.- Immunoreactivity of Alzheimer Amyloid Precursor Protein (APP) Specific Antisera with Platelet Granule Constituents.- Site of Formation of ss-Protein Amyloid Fibrils.- A Search for Vascular Amyloid Using A4 Amyloid Antibody Immunostain in CAA (Classic Methods) Negative Alzheimer's Cases.- A Variant of Gerstmann-Straussler-Scheinker Disease with ss-Protein Epitopes and Dystrophic Neurites in the Peripheral Regions of Prp-Immunoreactive Amyloid Plaques.- Antigenic Heterogeneity of Cerebral Amyloid Deposits in Alzheimer'S Disease.- Systemic Vascular Amyloidosis Associated with Alzheimer's Disease.- Pathological Changes in Hereditary Cerebral Hemorrhage with Amyloidosis - Dutch Type.- Hereditary Cerebral Hemorrhage with Amyloidosis - Dutch Type.- Peripheral Distribution of Dermatan Sulfate Proteoglycan (Decorin) in Amyloid Plaques and Their Presence in Neurofibrillary Tangles of Alzheimer's Disease.- Choroid Plexus Amyloid.- IX Diagnostics, Clinical and Therapeutic Aspects.- New Images of Clinical Amyloidosis.- Scintigraphic Imaging of Amyloidosis with 123Iodine Serum Amyloid P Component.- Longtime Follow Up of Patients with Al-Amyloidosis with MRI.- Detection of Autonomic Dysfunctions in Patients with Familial Amyloidotic Polyneuropathy (FAP) by Laser Doppler Method.- Non-Invasive in vivo Detection of Ab-Amyloidosis Using its Radiolabelled Precursor Protein.- Cardiac Involvement in Secondary Amyloidosis.- Imaging Hereditary Amyloidosis of Ostertag.- Computer-Aided Immunohistochemical Quantitation of Amyloid in Renal Biopsies.- Abdominal Fat Biopsy for Characterization of the Major Amyloid Fibril Proteins by Amino Acid Sequence Analysis.- Beta-2-Microglobulin Does Not Deposit in Abdominal fat Tissue of Long-Term Hemodialysis Patients.- Histopathologic Classification, Clinical Characteristics and Survival of 18 Patients with Inconclusive Clinical Data to Identify the AA Or Al Type of Their Systemic Amyloidosis.- Immunohistochemical Detection of Amyloid AA in Formaline-Fixed Paraffine-Embedded Rectal Biopsies with the Monoclonal Anti-Human SAA Antibody Reu.86.2.- Long Survival in Patients with Al Amyloidosis.- Secondary Systemic Amyloidosis (AA): Response and Survival in 64 Patients.- Renal Manifestations of Amyloidosis Complicated with Rheumatoid Arthritis.- Crp and SAA Serum Levels In Chronic Active Hepatitis.- Serum Amyloid a and C-Reactive Protein in the First 4 Weeks After Liver Transplantation.- Differential Influence of Glucocorticoids on CRP and SAA Serum Levels in Rheumatoid Arthritis and Polymyalgia Rheumatica.- Ocular Microangiopathy in Familial Amyloidotic Polyneuropathy (FAP) Type I.- Spectral Analysis of R-R Variability in Familial Amyloidotic Polyneuropaty, Andrade Type.- Microalbuminuria in Patients with Familial Mediterranean Fever.- Dopamine-ss-Hydroxylase in Familial Mediterranean Fever.- A Multicentric Study on Hemodialysis Amyloid Osteoarthoropathy in 747 Dialysis Patients.- Renal Transplantation in Renal Amyloid end-Stage Disease.- Effect of Continuous Colchicine Treatment in Familial Mediterranean Fever (FMF).- Treatment of Amyloidosis Associated Diarrhea with a Somatostatin Analogue.- Gastrointestinal Malabsorption in Familial Amyloidotic Polyneuropathy (FAP): Ursodeoxycolic Acid Absorption Test.- The Prevalence, Importance and Significance of Amyloidosis with Rheumatic Diseases in Turkey.- Cyclosporin Reduces the Incidence of Amyloid Disease in Casein Treated Mice.- X Special Session on Bio Assays and Standardization of Amyloid Proteins and Precursors.- Report of Special Session on Bioassays and Standardization of Amyloid Proteins and Precursors.- Identification of APO-SAA Isoforms in Man and Mouse.- Normal Lipoproteins Inhibit Binding of SAA-Rich Lipoproteins to Polyvinylchloride Surfaces.- Monoclonal Antibody Based Elisa for Human SAA.- Serum Amyloid P Component in Chronic Renal Failure and Dialysis.- Monoclonal Antibodies to Human Serum Amyloid P-Component.- Screening with Monoclonal Anti ss-Protein Antibody for Immunoreactivity in the Sera of Patients with Alzheimer's Disease.- XI Summary Sessions.- Summary Of Day 1: Overview.- Summary of Day 2: Amyloidosis: Molecular Insights and Cellular Blindspots.- Summary of Day 3: Overview.- List of Contributors.


PRODUCT DETAILS

ISBN-13: 9789401054508
Publisher: Springer
Publication date: December, 2014
Pages: 936
Weight: 1454g
Availability: Available
Subcategories: Biochemistry, Cardiovascular Medicine, Nephrology, Rheumatology
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