Main description:

The first and only source to offer an all-encompassing approach to the pathogenesis and treatment of thrombocytopenic disorders, this book reviews current information concerning thrombocytopenia due to diminished platelet production and accelerated immunologic and nonimmunologic platelet clearance, as well as a detailed review of medications that cause this disorder.

Contents:

THROMBOCYTOPENIA DUE TO DIMINISHED PLATELET PRODUCTION. Overview and Biology of Platelet Production. Thrombopoietin: Biology, Clinical Studies, and Potential as a Therapeutic Agent. Inherited Thrombocytopenias. Miscellaneous Thrombocytopenias Due to Decreased Platelet Production. THROMBOCYTOPENIA DUE TO EXCESSIVE PLATELET DESTRUCTION. Overview of Platelet Clearance Mechanisms. Immune Thrombocytopenic Purpura. Drug-Induced Thrombocytopenia. Heparin-Induced Thrombocytopenia. Neonatal alloimmune Thrombocytopenia. Thrombotic Microangiopathies: TTP and HUS. Thrombocytopenia in Pregnancy. Platelet Transfusion: Indications and Adverse Effects