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Principles of Molecular Cardiology
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Main description:

An easy-to-read survey of all the latest developments in molecular cardiologic research and therapy. The authors explain in a readable style the complex process of the heart's development, the molecular basis of cardiovascular diseases, and the translation of these research advances to actual clinical treatments. The expert information provided here serves as an invaluable building block for novel treatments of cardiovascular diseases and includes a comprehensive discussion of cardiac function and dysfunction, coronary artery disease, cardiac arrhythmias, vascular diseases, and risk factors for cardiovascular disease. These state-of-the-art approaches to molecular cardiologic research include critical discussion of such topics as the molecular events that regulate angiogenesis and the potential for angiogenic therapy, emerging therapies for arrhythmias, and a description of the molecular biology of aging and its impact on the cardiovascular system.


Contents:

Part I. Overview

Cardiovascular Genetics
Christopher Semsarian and Christine Seidman

Molecular Biology Applications in Cardiovascular Medicine
Eugene Yang, Scott M. Wasserman, Tatsuro Ishida, Raymond Tabibiazar, and Thomas Quertermous

Genomics and Its Application to Cardiovascular Disease
Robert Roberts

Gene Therapy and Cardiovascular Diseases
Yi Chu, Neal L. Weintraub, and Donald D. Heistad

Stem Cells and Progenitor Cells in Cardiovascular Disease
Jalees Rehman and Keith L. March

Part II. Myocardial Disease

Development of the Vertebrate Heart
Mabelle Ashe and David Bader

Inherited Myocardial Diseases
Elizabeth M. McNally

Receptor-Signaling Pathways in Heart Failure
Shayela Suvarna, Liza Barki-Harrington, Miwako Suzuki, Philippe Le Corvoisier, and Howard A. Rockman

Recent Insights into the Molecular Pathophysiology of Viral Myocarditis
Tony Tran, Roger D. Rossen, and Douglas L. Mann

Genetic Underpinnings of Cardiogenesis and Congenital Heart Disease
Vidu Garg and Deepak Srivastava

Part III. Coronary Artery Disease

Coronary Artery Development
Mark W. Majesky

Atherosclerosis
George A. Stouffer

Antiplatelet Drugs
Karlheinz Peter

Myocardial Infarction
D. Douglas Miller and Steven C. Herrmann

Transplant Arteriopathy: Pathology, Pathogenesis, and Prospects for Treatment
Joannis Vamvakopoulos, Einari Aavik, Daniel du Toit, Pekka Hayry, and Minnie Sarwal

Thrombolysis: Scientific Basis for Current Therapy
Guy L. Reed III

Coronary Restenosis
Julius Aitsebaomo, Martin Moser, Susan Smyth, and Cam Patterson

Part IV. Arrhythmias

Induction and Patterning of Purkinje Fiber Network
Takashi Mikawa, Robert G. Gourdie, Kimiko Takebayashi-Suzuki, Nobuyuki Kanzawa, DavidJ. Pennisi, Clifton P. Poma, and Maxim Shulimovich

Mechanisms of Sudden Cardiac Death
Wayne E. Cascio

Gene Therapy for Cardiac Arrhythmias
J. Kevin Donahue and Eduardo Marban

Genetics and Arrhythmias
Kui Hong and Ramon Brugada

Part V. Vascular Diseases

Therapeutic Angiogenesis for Ischemic Vascular Disease
Jai Pal Singh and J. Anthony Ware

Nitric Oxide in Cardiovascular Biology and Pathophysiology
Marshall A. Corson

Vasculitis
Ronald J. Falk and J. Charles Jennette

Primary Pulmonary Hypertension
Evangelos D. Michelakis and Stephen L. Archer

The Molecular Basis of Cerebrovascular Malformations
Douglas A. Marchuk

Thrombotic Vascular Disease
Stephan Moll and Gilbert C. White II

Part VI. Risk Factors

Risk Factors
Ngoc-Anh Le and W. Virgil Brown

Vascular Aging: From Molecular to Clinical Cardiology
Samer S. Najjar and Edward G. Lakatta

Oxidative Stress
Nageswara R. Madamanchi and Marschall S. Runge

Diabetes Mellitus: An Important Cardiovascular Risk Factor
David R. Clemmons

Vascular Inflammation as a Cardiovascular Risk Factor
Allan R. Brasier, Adrian Recinos III, and Mohsen S. Eledrisi

Index


PRODUCT DETAILS

ISBN-13: 9781627038072
Publisher: Springer (Humana Press Inc.)
Publication date: November, 2014
Pages: 632
Weight: 1568g
Availability: Available
Subcategories: Cardiovascular Medicine
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