Main description:

This book is a thorough, practical review of the challenges facing clinicians treating skin microbes and how to combat these therapeutic dilemmas. It expresses the critical public health concern of antimicrobial resistance and shows how microorganisms are developing the ability to halt the progress of antimicrobials like antibiotics, antivirals, and antifungals. Chapters are grouped together in five sections for ease of use. The first three sections of the book convey foundational information on the mechanisms of antibiotics, antivirals, and antifungals resistance, as well as the implications of lack of vaccination. The fourth section then turns to the specifics of drug resistance for protozoan and helminth infections focusing primarily on initial and subsequent resistance to treatment. The book closes with a discussion on the potential solutions of innovative therapy including new delivery mechanisms, broad-spectrum antibiotics, phytocompounds, and biofilms. Chapters feature magnified, microscopic photos for identifying structures as they appear on the skin. Part of the Updates in Clinical Dermatology series, Overcoming Antimicrobial Resistance of the Skin is an important resource relevant during the COVID-19 pandemic, and is written for all medical healthcare professionals.

Contents:

Section 1: Emerging Bacterial Resistance to Antibiotics Chapter 1: Mechanisms of Bacterial Resistance Chapter 2: Emerging Bacterial Infections Chapter 3: Reemerging Bacterial InfectionsSection 2: Emerging Resistance to Antivirals Chapter 4: Mechanisms of Non-retroviral Resistance Chapter 5: Mechanisms of Retroviral Resistance Chapter 6: Emerging Viral Infections Chapter 7: Reemerging Viral Infections: Implications of Lack of Vaccination Section 3: Emerging Resistance to Antifungals Chapter 8: Mechanisms of Antifungal Resistance Chapter 9: Emerging and Reemerging Fungal InfectionsSection 4: Emerging Resistance to Drugs for Protozoan and Helminth Infections Chapter 10: Mechanisms of Anti-Protozoan/Helminth Drug Resistance Chapter 11: Emerging and Reemerging Protozoan/Helminth InfectionsSection 5: Innovative Therapies on the Forefront Chapter 12: Phage Therapy Chapter 13: The Role of Biofilms Chapter 14: New Classes of Broad-spectrum Antimicrobials Chapter 15: Phytocompounds Chapter 16: Summary