Main description:

This seventh edition of Medical Immunology, now in a full-color presentation, continues to provide a succinct clinical review of the human response to infection while being firmly grounded in science. The authors, distinguished and experienced educators, have been able to anticipate readers' conceptual challenges and use illustrations, diagrams, and algorithms throughout to simplify complex concepts. With an emphasis on clinical applications, methodological advances, immunological diseases, and innovative interventions, this tried and true guide navigates readers through state-of-the-sciences technologies and demonstrates their implementation in the day-to-day clinical practice of immunology.

Key Features

Stresses both the basic scientific concepts and clinical correlations to medical practice.

Progresses logically from normal immune function to abnormalities and clinical diseases.

Reviews the diagnosis, pathogenesis, and management of autoimmune diseases in a concise, manageable and visual manner

Continues to be the only current medically-focused immunology text available

Provides a succinct review of human response to infection with a focus on diagnostic and clinical immunology

Contents:

Introduction. Leukocytes and lymphoid tissues: The framework of the immune system. Major histocompatibility complex. Adaptive immune response: Antigens, lymphocytes, and accessory cells. Immunoglobulins: Structure and diversity. Immunoglobulins: Metabolism and biological properties. Genetics of immunoglobulins: Ontogenic, biological, and clinical implications. Antigen-antibody reactions. The complement system in health and disease. Monocyte and lymphocyte membrane markers: Ontogeny and clinical significance. Cell-mediated immunity. Adaptive humoral immunity and immunoprophylaxis. Phagocytic cells and their functions. Anti-infectious innate and adaptive immune responses. Diagnostic applications of immunology. Tolerance and autoimmunity. Organ-specific autoimmune diseases. Systemic lupus erythematosus. Rheumatoid arthritis. Overview of hypersensitivity. IgE-mediated (immediate) hypersensitivity. Immunohematology. Pathogenic role of antigen-antibody complexes. Immune system modulators. Transplantation immunology. Tumor immunology. Lymphocyte and plasma cell malignancies. Diagnosis of immune deficiency diseases. Primary immunodeficiency diseases. AIDS and other acquired immunodeficiencies