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Long non coding RNAs in Breast Cancer Prevention and Treatment
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Main description:

This volume, with contributions from the most recognized experts in preventive strategies in breast cancer, presents the accepted as well as the novel ideas that have been introduced for the prevention of breast cancer.

There is no single preventive agent that can stop the incidence of breast cancer—the malignant disease most frequently diagnosed in women of all races and nationalities. Furthermore, its incidence around the globe is increasing in industrialized countries. The worldwide incidence of breast cancer has increased 30-40% since the 1970s, reaching an excess of 1,390,000 new cases and a mortality of more than 460,000 cases in 2015. Therefore, what is needed is the development of rational strategies for the prevention of this fatal disease.


Feature:

Explores both growth-inhibitory and mucin-depleting effects of bromelain and N-acetylcysteine, on their own or in combination, in cancer

Skillfully reviews the pathophysiological aspects of the mucin glycoproteins in malignancies

Provides an updated account of the status of bromelain and N-acetylcysteine in cancer therapy

Develop the idea of using these two drugs as a combination formulation for mucin-depleting effects


Back cover:

This volume, with contributions from the most recognized experts in preventive strategies in breast cancer, presents the accepted as well as the novel ideas that have been introduced for the prevention of breast cancer.

There is no single preventive agent that can stop the incidence of breast cancer—the malignant disease most frequently diagnosed in women of all races and nationalities. Furthermore, its incidence around the globe is increasing in industrialized countries. The worldwide incidence of breast cancer has increased 30-40% since the 1970s, reaching an excess of 1,390,000 new cases and a mortality of more than 460,000 cases in 2015. Therefore, what is needed is the development of rational strategies for the prevention of this fatal disease.


Contents:

1 The paradigms in breast cancer prevention.- 2 The role genistein in breast cancer prevention.- 3 The role of Omega 3 in breast cancer prevention.- 4 Is there a role for Raloxifene and Tamoxifene for the prevention of breast cancer?.- 5 Aromatase inhibitors for breast cancer prevention.- 6 Inhibition of the estrogen metabolism pathways as a preventive strategy in hormone dependent cancer.- 7 The molecular mechanisms of the dual effect of pregnancy in risk and prevention of breast cancer.- 8 Beyond aspirin in breast cancer prevention.- 9 Role of diet in the prevention of breast cancer.- 10 Vaccination against breast cancer and its role in prevention. 


PRODUCT DETAILS

ISBN-13: 9783319269634
Publisher: Springer (Springer International Publishing)
Publication date: May, 2019
Pages: 302
Availability: Not yet available
Subcategories: Oncology

MEET THE AUTHOR

Jose Russo, MD, FACP, is Professor and Senior Member, Fox Chase Center Center-Temple Health, Director of the Breast Cancer and the Environment Research Center, Fox Chase Cancer Center, Director, Irma H. Russo, MD-Breast Cancer Research Laboratories, Fox Chase Cancer Center, Adjunct Professor of Pathology and Cell Biology, Jefferson Medical College, and Professor of Biochemistry, Temple Medical School.

Maria Barton, MS, is a PhD Candidate in Biochemistry, Temple University/Fox Chase Center, The Irma H. Russo, MD-Breast Cancer Research Laboratories.

Julia Santucci-Pereira, PhD, is Researcher, Fox Chase Cancer Center, The Irma H. Russo, MD-Breast Cancer Research Laboratories.

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