Main description:

"Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes" provides a summary of the current knowledge of these organelles which occur in unicellular, often parasitic organisms, including human pathogens. These organelles exhibit a variety of structures and functions. This work describes properties such as protein import, structure, metabolism, adaptation, proteome and their role in drug activation and resistance. Further topics include organelle evolution and biogenesis.

Contents:

Introduction, history etc.., Miklos Muller, The Rockefeller University, USA,- Anaerobic Eukaryotes in Persuit Normality: the Eolution of mitochondria-derived organelle, William Martin, Germany,- Protein Import into Hydrogenosomes and Mitosomes, Abhijith Radhakrishna Makki, Jan Tachezy, Pavel Dolezal,- Structure of the Hydrogenosome (morphogenesis, electron microscopy, comparison of various hydrogenosomes..), Marlene Benchimol, Brasil,- Hydrogenosomes of anaerobic ciliates, Johannes H.P. Hackstein, The Netherlands,- Metabolism of trichomonad hydrogenosomes (energy metabolism, electron transport...), Ivan Hrdy, Charles University, Czech Republic,- Hydrogenosomes of anaerobic chytrids (Neocallimastix, Piromyces), L. Tielens, J. Hellemond, F. Voncken, J. Heckstein,- The proteome of T. vaginalis hydrogenosomes, Petr Rada Charles University, Czech Republic,- Mitosomes in parasitic protists: Entamoeba histolytica, Giardia intestinalis, microsporidia..., J. Tachezy, Pavel Dolezal,- Remnant mitochondria of Cryptosporidium parvum, Anastasios Tsaousis, UK,- Mitochondrion-derived organelles in free-living protists, A. Roger M. Kolisko,- Organisms without mitochondria, how it may happen?, V. Hampl.