Main description:

A concise compilation of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. For each class of drugs the authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents.

Comprehensive and easy-to-use, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and toxicologists with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.

Contents:

Part I. Central Nervous System Drugs

Chapter 1: Drug Interactions with Benzodiazepines: Epidemiologic Correlates with Other CNS Depressants and In Vitro Correlates with Inhibitors and Inducers of Cytochrome P450 3A4
David E. Moody

Chapter 2: Antiepileptic Drugs
Nathan L. Kanous II and Barry E. Gidal

Chapter 3: Opioids and Opiates
Seyed-Adel Moallem, Kia Balali-Mood, and Mahdi Balali-Mood

Chapter 4: Monoamine Oxidase Inhibitors and Tricyclic Antidepressants
Terry J. Danielson

Chapter 5: Selective Serotonin Reuptake Inhibitors
Mojdeh Mozayani and Ashraf Mozayani

Chapter 6: Antipsychotic Drugs and Interactions: Implications for Criminal and Civil Litigation
Michael Welner

Part II. Cardiovascular Drugs

Chapter 7: Cardiovascular Drugs
Johann Auer

Part III. Antibiotics

Chapter 8: Antimicrobial Drugs
Amanda J. Jenkins and Jimmie L. Valentine

Chapter 9: Drug Interactions with Medications Used for HIV/AIDS
Michael Frank

Part IV. Nonsteroidal Antiinflammatory Drugs

Chapter 10: Nonsteroidal Antiinflammatory Drugs: Cyclooxygenase Inhibitors, Disease-Modifying Antirheumatic Agents, and Drugs Used in Gout
Imad K. Abukhalaf, Daniel A. von Deutsch, Mohamed A. Bayorh, and Robin R. Socci

Part V. Environmental and Social Pharmacology

Chapter 11: Food and Drug Interactions
Shahla M. Wunderlich

Chapter 12: Alcohol and Drug Interactions
A. Wayne Jones

Chapter 13: Nicotine and Tobacco
Edward J. Cone, Reginald V. Fant, and Jack E. Henningfield

Chapter 14: Anabolic Doping Agents
Daniel A. von Deutsch, Imad K. Abukhalaf, and Robin R. Socci

Part VI. Legal Aspects

Chapter 15: Drug Interaction Litigation
Stephen A. Brunette

Chapter 16: Psychotropic Medications and Crime: The Seasoning of the Prozac Defense
Michael Welner

Index