Main description:

v. K. Moudgil, Series Editor INTRODUCTION TO VOLUME 2 ...xiii Edward J Pavlik ABOUT VOLUME 1 ...xvi Edward J Pavlik CONTRIBUTORS ...xix Part I: ESTROGEN AND PROGESTIN PHYSIOLOGICAL FuNCTION 1. Pituitary and Brain Actions of Estrogen and Progesterone in the Regulation of Primate Prolactin Secretion...3 C. L. Bethea, S. G. Kohama, and M. Pecins-Thompson 2. Saccharomyces cerevisiae As a Model System to Study Steroid Hormone Receptors ..." 47 Brandee L. Wagner and Donald P McDonnell 3. Physiological Findings from Transgenic Mouse Models with Altered Levels of Estrogen Receptor Expression...69 John F Couse, Vicki L. Davis, and Kenneth S. Korach Part II: MOLECULAR BIOLOGY OF STEROID RECEPTORS AND GENE EXPRESSION 4. New Models and Insights in Steroid Hormone Action ...101 Lisa L. Wei 5. A Role for Progesterone in Multidrug Resistance ...123 Shyamali Mallick and Susan Band Horwitz 6. Dominant Negative Activity by Estrogen and Progesterone Receptors ...153 Paul M. Yen 7. Estrogen and Progesterone Receptors in Human Endometrial Cancer ...169 Kian Behbakht and Jeff Boyd x Contents Part m: FACTORS ENHANCING RECEPTOR FuNCllON 8.
Facilitated Binding of Steroid Hormone Receptors to Target DNA by the Chromatin High-Mobility Group Protein-1: Protein Manipulation of DNA Structure ...191 Dean P. Edwards and Paul Prendergast 9. Use of FK506 and Its Analogs in Studying Progesterone Signaling ...217 Ping-Kaung Ku Tai and Lee E. Faber KEYWORD INDEX ...231 Foreword These two volumes on Estrogens, Progestins, and Their Antagonists repre- sent a thematic extension of the series, Hormones in Health and Disease.

Contents:

I: New Applications and Concepts Involving Estrogens and Progestins.- 1. Benefits and Risks of Hormone Replacement Therapy.- 2. Phytoestrogen Effects in Humans Relative to Risk for Cardiovascular Disease, Breast Cancer, Osteoporosis, and Menopausal Symptoms.- 3. Dietary Indoles with Antiestrogenic Activity in Common Vegetables and Their Implications.- 4. Treatment for Infertility and Risk of Female Cancers.- 5. Antiestrogen Resistance in Human Breast Cancer.- 6. Evolving Therapies for Prostatic Carcinoma, Encompassing Orchiectomy, Estrogens, and Estramustine.- 7. Regulatory Aspects of Estrogens and Progestins in Human Food: Past, Present, and Future.- II: Novel Hormonal Ligands.- 8. Estrogen and Progestin Radiopharmaceuticals for Imaging Breast Cancer.- 9. The Utility of Fluorescent Estrogens for Receptor Imaging.- 10. Comparative Review of Recently Introduced Oral Contraceptives Containing Norgestimate, Desogestrel and Gestodene and Older Oral Contraceptives.- 11. Antiprogestins: Past, Present, and Future.- Keyword Index.