Main description:

Cancer is a disease related to ageing, and the proportion of senior patients increases worldwide. While the proportion of persons beyond age 70 is still small in developing countries, their numerous population means that there are more "elderlies" in India than in Europe. This book reflects the state of the art in the management of senior adults with cancer. This handbook leaves ample space for chapters that help in the delicate decision making process, which should lead to the best therapy, adapted not only to the disease but also to the person who suffers from it.

Contents:

Introduction Defining the Elderly Biology of Aging and Changes in Organ Function Changes in Cognition Cancer and Aging Clinical Aspects Further Reading Cancer Epidemiology Introduction Population Demographics Cancer Demographics Society-Related Problems Conclusions Further Reading Evaluation of the Senior Cancer Patient: Comprehensive Geriatric Assessment and Screening Tools for the Elderly Introduction Short Screening Tools The Vulnerable Elders Survey 13 MGA Packages Further Reading Frailty in the Elderly Frailty in the Elderly The Impact of Frailty on Cancer Assessment of Frailty Conclusion Further Reading Surgical Treatment Introduction Indications for Surgery Patients Selection Outcomes Survival Palliation Side Effects Conclusion Further Reading Radiotherapy in the Elderly Cancer Patient Indications for Radiotherapy in the Elderly Side Effects of Radiotherapy in the Elderly (Acute and Late) Efficacy and Outcome of Radiotherapy in the Aging Palliative Setting: Toxicity and Efficacy Ratio Curative Setting: Combinations of Chemotherapy and Radiotherapy Selection Criteria for Radiotherapy in the Elderly Conclusions Further Reading Hormonal Anticancer Treatment in the Senior Cancer Patient Introduction Breast Cancer Prostate Cancer Further Reading Cytotoxic and Targeted Anticancer Treatment in the Senior Cancer Patient Introduction Chemotherapy in Senior Adults Targeted Therapies in Senior Adults Further Reading Treatment of Lymphoma in the Elderly Population Introduction Diagnosis and Prognosis Treatment Conclusions Further Reading Management of Myeloproliferative Diseases in Senior Patients Diagnosis and Classification of Myeloproliferative Disorders Treatment Strategies of MPD in the Senior Patient Conclusions Future Outlook Further Reading Myelodysplastic Syndromes in the Senior Patient The Relevance of Myelodysplastic Syndromes in the Elderly Classification and Risk Scoring in MDS Age-Adjusted Models and Assessment in Elderly MDS Patients Treatment Options in Elderly MDS Patients Future Perspectives Further Reading Breast Cancer in the Senior Patient Introduction Early Breast Cancer Metastatic Breast Cancer Conclusions Further Reading Lung Cancer in the Elderly Introduction Early Non-Small Cell Lung Cancer in the Elderly Advanced Non-Small Cell Lung Cancer in the Elderly Small Cell Lung Cancer in the Elderly Palliative Treatment in Elderly Lung Cancer Patients Conclusion Further Reading Colorectal Cancer Introduction Adjuvant Chemotherapy Metastatic Disease Conclusion Further Reading Prostate Cancer Introduction and General Background Treatment of Localized Prostate Cancer in Senior Adult Patients Treatment of Metastatic Prostate Cancer in Senior Adult Patients Conclusion Acknowledgments Further Reading Bladder Cancer Incidence and Mortality Etiology and Risk Factors Pathology Natural History and Tumor Biology Signs and Symptoms Imaging, Cystoscopy, and Urinary Cytopathology Staging Treatment of NMIBC Surgical Treatment Radiotherapy Organ-Sparing Treatments Systemic Chemotherapy Prognosis of BC Follow-Up Further Reading Gynecological Cancer in the Senior Patient Introduction Cervical Cancer Uterine Cancer Special Types of Endometrial Malignancy Vaginal Cancer Vulvar Cancer Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer Conclusion Further Reading Head and Neck Cancer in the Elderly Introduction Surgery Radiotherapy Chemotherapy Targeted Therapies Conclusion Further Reading Renal Cell Cancer Introduction Surgery in the Senior Cancer Patient Systemic Therapy of Metastatic Renal Cell Carcinoma in the Senior Cancer Patient Patient-Focused Approach Conclusion Further Reading Psychological Problems in Older Cancer Patients Introduction Depression Anxiety Conclusions Further Reading Social and Ethical Aspects Introduction Respect Admiration Attention Information Protection Diagnosis Care Time Caution Freedom Further Reading The Role of the Multidisciplinary Team Introduction The Assessment of Age Polypharmacy Management of the Caregiver Function of the Team Conclusions and Perspectives Further Reading