Main description:

This second edition volume expands on the previous edition with discussions on the latest techniques used to study synaptic transmissions. The chapters in this book are organized into six parts. Part One looks at the basic concepts, such as extracellular and intracellular recordings, and spatiotemporal effects of synaptic currents. Part Two describes the recording of synaptic currents, such as measuring kinetics of synaptic current and measuring reversal potentials. Part Three discusses basic experimentations of synaptic transmission and covers run-up and run-down, and amplitude. Parts Four and Five cover experimentations with computational components and molecular and visual components, such as measurement of a single synapse and electrophysiological and visual tags. Part Six explores in vivo recordings and talks about general considerations for in vivo exploration of synaptic plasticity. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Authoritative and thorough, Electrophysiological Analysis of Synaptic Transmission, Second Edition is a valuable resource that introduces graduate students and postdoctoral fellows to important topics in this field and also expands these topics to practical electrophysiological approaches.

Contents:

About the Editors...
Preface...
Table of Contents...
Contributing Authors...

Part I Basic Concepts

1. Extracellular and Intracellular Recordings
Nicholas Graziane and Yan Dong

2. Electrical Theory
Nicholas Graziane and Yan Dong

3. Amplifiers
Nicholas Graziane and Yan Dong

4. Salt Environment
Nicholas Graziane and Yan Dong

5. Patch Pipettes (Micropipettes)
Nicholas Graziane and Yan Dong

6. Spatiotemporal Effects of Synaptic Current
Nicholas Graziane and Yan Dong

7. Perforated Patch
Nicholas Graziane and Yan Dong

Part II Recording of Synaptic Current

8. Isolation of Synaptic Current
Nicholas Graziane and Yan Dong

9. Fast and Slow Synaptic Currents
Nicholas Graziane and Yan Dong

10. Measuring Kinetics of Synaptic Current
Nicholas Graziane and Yan Dong

11. Measuring Presynaptic Release Probability
Nicholas Graziane and Yan Dong

12. Long-Term Measurements
Nicholas Graziane and Yan Dong

13. Measuring Reversal Potentials
Nicholas Graziane and Yan Dong

Part III Basic Experimentations of Synaptic Transmission

14. Amplitude
Nicholas Graziane and Yan Dong

15. Pre- vs. Post-Synaptic Effect
Nicholas Graziane and Yan Dong

16. Run-Up and Run-Down
Nicholas Graziane and Yan Dong

17. Kinetics of Synaptic Current
Nicholas Graziane and Yan Dong

Part IV Experimentations with Computational Components

18. Measurement of a Single Synapse
Nicholas Graziane and Yan Dong

19. Measurement of Silent Synapses
Nicholas Graziane and Yan Dong

20. Dendritic Patch
Nicholas Graziane and Yan Dong

Part V Experimentations with Molecular and Visual Components

21. Electrophysiological and Visual Tags
Nicholas Graziane and Yan Dong

Part VI In Vivo Recordings

22. Extracellular Recordings
Nicholas Graziane and Yan Dong

23. General Considerations for In Vivo Exploration of Synaptic Plasticity
Xiyu Zhu and Anthony Grace

24. Technical Considerations for In Vivo Electrophysiology
Xiyu Zhu and Anthony Grace

Subject Index List...