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Crimean-Congo Hemorrhagic Fever
A Global Perspective
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Main description:

Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease associated with severe hemorrhagic manifestations. CCHF has been referred to as the "Asian Ebola." However, in fact, the disease is one of the most widely distributed tick-borne diseases in the world, occurring in Africa, Asia, Europe, and the Middle East. This volume covers major aspects of this important disease and the virus which causes it. Chapters are written by leading experts in their fields and detail historical, public health, epidemiological, and clinical aspects of CCHF and the genetics and molecular biology of the virus. Additional chapters focus on disease control, tick vectors and infection among animals, both natural and experimental.

This book will be of interest to virologists, microbiologists, medical entomologists, infectious disease physicians, epidemiologists, public health specialists, veterinary scientists, public health policy makers, journalists, and medical educators.


Geographically the most extensively reported viral hemorrhagic fever

Covers Asian ebola

Discusses nosocomial zoonosis (a zoonosis that could also be an agent for hospital infection)

Outlines the most significant epidemics in recent years

Covers the only viral hemorrhagic fever in Europe


Preface: Onder Ergonul and Chris A. Whitehouse Section I: Introduction and Historical Perspectives
1. Introduction: Onder Ergonul and Chris A. Whitehouse
2. A Historical Perspective of Infectious Diseases with Reference to Crimean-Congo Hemorrhagic Fever: Berna Arda and Ahmet Aciduman
3. Personal Reflections: Jack Woodall Section II: Etiologic agent
4. Molecular Biology of the Crimean-Congo Hemorrhagic Fever Virus: Ramon Flick
5. Molecular Epidemiology, Genomics, and Phylogeny of the Crimean-Congo Hemorrhagic Fever Virus: Roger Hewson Section III: Epidemiology and ecology
6. Crimean-Congo Hemorrhagic Fever in Turkey: Zati Vatansever, Ramazan Uzun, Agustin Estrada-Pena, Onder Ergonul
7. Crimean-Congo Hemorrhagic Fever in the Balkans: Tatjana Avsic-Zupanc
8. Crimean-Congo Hemorrhagic Fever in Iran: Sadegh Chinikar
9. Crimean-Congo Hemorrhagic Fever in Russia and the Former Soviet Union: A.M. Butenko and G.G. Karganova
10. Crimean-Congo Hemorrhagic Fever CCHF in the Xinjiang Uygur Autonomous Region of Western China: Masayuki Saijo
11. Crimean-Congo Hemorrhagic Fever in South Africa: Felicity J. Burt and Robert Swanepoel
12. Role of Ticks in the Transmission of Crimean-Congo Hemorrhagic Fever Virus: Mike Turell
13. Infection among Animals: Aysegul Nalca and Chris A. Whitehouse
14. Ecology of Disease and the Role of Climate Change: Sarah Randolph and David J. Rogers
15. Predicative Models of Infection: Ben Cooper Section IV: Clinical Features and Pathogenesis
16. Clinical and Pathologic Features of Crimean-Congo Hemorrhagic Fever: Onder Ergonul
17. Pathogenesis of Crimean-Congo Hemorrhagic Fever and Correlation with other Viral Hemorragic Fevers: Mike Bray
18. Laboratory Diagnosis of Crimean-Congo Hemorrhagic Fever: Herve Zeller
19. Treatment of Crimean-Congo Hemorrhagic Fever
19.1. Current Therapy: Ribavirin Use and Hematological Support: Onder Ergonul
19.2. Old and New Treatment Strategies: Ali Mirazimi
19.3. Antibodies to CCHFV for Prophylaxis And Treatment: Mitko Dimitrov

Section V: Prevention and Control
20. Risk Groups and Control of Tick Vectors: Chris A. Whitehouse
21. Estimates and Prevention of Crimean Congo Hemorrhagic Fever Risks for Health Care Workers: Arnaud Tarantola, Onder Ergonul, Pierre Tattevin
22. International Surveillance and Control of Crimean-Congo Hemorrhagic Fever Outbreaks: Pierre Formenty, Glenn Schnepf , Fernando Gonzalez-Martin, and Zhenqiang Bi Section VI: Remaining questions and future research
Future Research: Onder Ergonul and Chris A. Whitehouse
Frequently Asked Questions Index


ISBN-13: 9789048175383
Publisher: Springer (Springer Netherlands)
Publication date: October, 2010
Pages: 354
Weight: 539g
Availability: POD
Subcategories: Infectious Diseases, Microbiology
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