Contents:

Cocaine: 1884-1974.- Neural Substrates Mediating Amphetamine Responses.- Mesolimbic and Extrapyramidal Sites for the Mediation of Stereotyped Behaviour Patterns and Hyperactivity by Amphetamine and Apomorphine in the Rat.- Behavioral Effects of Amphetamine in Brain Damaged Animals: Problems in the Search for Sites of Action.- Basic Considerations on the Role of Concertedly Working Dopaminergic, Gaba-Ergic, Cholinergic and Serotonergic Mechanisms within the Neostriatum and Nucleus Accumbens in Locomotor Activity, Stereotyped Gnawing, Turning and Dyskinetic Activities.- Release of Neurotransmitters from the Brain in Vivo by Amphetamine, Methylphenidate and Cocaine.- Distribution and Metabolism of Amphetamine in Tolerant Animals.- Changes in Brain Catecholamines Induced by Long-Term Methamphetamine Administration in Rhesus Monkeys.- Neurobiological Antagonism of Cocaine by Lithium.- On Food Deprivation in Relation to Amphetamine Tolerance.- Cocaine: Distribution and Metabolism in Animals.- Behavioral Effects of Cocaine--Metabolic and Neurochemical Approach.- Small Vessel Cerebral Vascular Changes Following Chronic Amphetamine Intoxication.- Enhancement of Cocaine-Induced Lethality by Phenobarbital.- Changes in Neuronal Activity in the Neostriatum and Reticular Formation Following Acute or Long-Term Amphetamine Administration.- Amygdala Hyperspindling and Seizures Induced by Cocaine.- Sensitization to Cocaine Following Chronic a Ministration in the Rat.- Progressive Changes in Behavior and Seizures Following Chronic Cocaine Administration: Relationship to Kindling and Psychosis.- Cocaine: Discussion on the Role of Dopamine in the Biochemical Mechanism of Action.- Chronic Administration of Stimulant Drugs: Response Modification.- Differential Effects of Serotonin Depletion on Amphetamine-Induced Locomotion and Stereotypy.- Role of Monoamine Neural Pathways in d-Amphetamine- and Methylphenidate-Induced Locomotor Activity.- The Effects of Cocaine on the Aggressive Behavior of Mice, Pigeons and Squirrel Monkeys.- Changes in Individual and Social Behavior Induced by Amphetamine and Related Compounds in Monkeys and Man.- Reinforcement of Behavior by Cocaine Injections.- A Comparison of Cocaine and Diethylpropion under Two Different Schedules of Drug Presentation.- A Preference Procedure That Compares Efficacy of Different Intravenous Drug Reinforcers in the Rhesus Monkey.- The Effects of Response Contingent and Non-Contingent Shock on Drug Self-Administration in Rhesus Monkeys.- Drug-Maintained Performance and the Analysis of Stimulant Reinforcing Effects.- Acute Systemic Effects of Cocaine in Man: A Controlled Study of Intranasal and Intravenous Routes of Administration.- Cocaine: Blood Concentration and Physiological Effect after Intranasal Application in Man.- Physiological and Behavioral Effects of Intravenous Cocaine in Man.- Effects of Intravenous Cocaine on MHPG Excretion in Man.- Psychologic Test Responses and Methylphenidate.- The Comparative Psychotogenic Effects of L-DOPA and ET-495.- Structure-Activity Relationships of Several Amphetamine Drugs in Man.- Author Index.