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Chemical Genomics and Proteomics
Pharmacological Chemistry for the Identification of Protein Targets
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Contents:

PART 1 FRONTIERS IN CHEMICAL GENOMICS Chemical Genetics -- discovery of gene functions by small molecular weight compounds Chemical Biology -- crossroads of chemistry and biology Potentials of Chemical Genomics and Proteomics for drug discovery: promises and pitfalls PART 2 REGULATORY NETWORKS AND PATHWAYS Tyrosin kinases and their selective inhibitors Recent advances in protein interaction networks in inflammatory processes The Wut--Catenin--Pathway in mammalian cells: modulation and simulation PART 3 SMALL MOLECULE WEIGHT LIBRARIES The natural products pool Peptide derivative libraries Peptidomimetics libraries Microbial secondary metabolites PART 4 CHEMOINFORMATICS Virtual screening for lead structures Navigating chemical space for biology and medicine High throughput screening for kinase modulators PART 5 STRUCTURAL BIOLOGY OF PROTEIN TARGETS Structure function relations analysed by X--ray crystallography NMR analysis as a drug discovery tool Structural screening of fragments into quality leads Modeling of receptor flexibility PART 6 CHEMICAL GENETICS IN EXPLORATION OF BIOLOGY Chemical Genetics for studies of cellular differentiation Probing and controlling intracellular processes with small molecules Multi component therapeutics for networked systems


PRODUCT DETAILS

ISBN-13: 9783527314720
Publisher: John Wiley & Sons Ltd (Wiley-VCH Verlag GmbH)
Publication date: December, 2050
Pages: 400
Weight: 652g
Availability: Contact supplier
Subcategories: Pharmacology

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