The field of bioinformatics continues to develop energetically. This comprehensive second edition covers new findings using the successful formula of the original text. Bioinformatics: An Introduction is structured into three parts devoted to Information, Biology and Applications. Every section of the book has been thoroughly updated, and expanded where relevant, to take account of significant new discoveries and realizations of the importance of certain concepts. Furthermore new chapters on Algorithms, Data Processing and Biotechnology have been added. Emphasis is placed on the underlying fundamentals and acquisitions of a broad and comprehensive grasp of the field as a whole. This second edition is intended to be a complete study companion for the advanced undergraduate or graduate student. It is self-contained, bringing together the multiple disciplines necessary for a profound grasp of the field into a coherent whole, allowing the reader to gain much insight into the state of art of bioinformatics.
Introduction. Part I: Information.- The Nature of Information.- The Transmission of Information.- Sets and Combinatorics.- Probability and Likelihood.- Randomness and Complexity.- Systems, Networks and Circuits.- Algorithms.- Part II: Biology.- Introduction to Part II.- The Nature of Living Things.- The Molecules of Life.- Part III: Applications.- Introduction to Part III.- Genomics.- Proteomics.- Interactomics.- Metabolomics and Metabonomics.- Medical Applications.- The Organization of Knowledge.- Bibliography.