Main description:

This book discusses the latest findings in the fields of biofilm, pilonidal cysts and sinuses. The first part provides detailed information on biofilm formation, antibiofilm properties and activity as well as their potential clinical application in wound management. The second part then examines pilonidal sinus disease and the surgical treatment options. Written by leading experts in the field, the book is a valuable resource for beginners and experienced surgeons alike.

Contents:

PART 1: BIOFILMBIOFILM: HISTORY, CAUSE AND TREATMENT.- HOST ENVIRONMENTAL SIGNALS AND EFFECTS ON BIOFILM FORMATION.- CHRONIC WOUND BIOFILM MODEL.- COMBATING BIOFILMS IN THE CHRONIC WOUND.- BIOFILM: CLINICAL EXPERIENCE.- MIXED-SPECIES BIOFILM COMPROMISES WOUND HEALING BY DISRUPTING EPIDERMAL BARRIER FUNCTION.- ANTI-BIOFILM AGENTS.- ANTI-BIOFILM PROPERTIES OF WOUND DRESSING INCORPORATING NONRELEASE POLYCATIONIC ANTIMICROBIALS.- ANTI-BIOFILM PEPTIDES AS A NEW WEAPON IN ANTIMICROBIAL WARFARE.- DILUTED HONEY INHIBITS BIOFILM FORMATION: POTENTIAL APPLICATION IN URINARY CATHETER MANAGEMENT?.- ANTIBIOFILM EFFICACY OF HONEY AND BEE-DERIVED DEFENSIN-1 ON MULTI-SPECIES WOUND BIOFILM.- GENES ENCODING ADHESION FACTORS AND BIOFILM FORMATION IN METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS IN MOROCCO.- ANTI-BIOFILM ACTIVITY OF BACTERIOPHAGES - MECHANISMS AND IMPACT ON CLINICAL PRACTICE.- SERRATIA SECONDARY METABOLITE PRODIGIOSIN INHIBITS PSEUDOMONAS AERUGINOSA BIOFILM DEVELOPMENT BY PRODUCING REACTIVE OXYGEN SPECIES THAT DAMAGE BIOLOGICAL MOLECULES.- ENHANCED INHIBITION OF BACTERIAL BIOFILM FORMATION AND REDUCED LEUKOCYTE TOXICITY BY CHLORAMPHENICOL: -CYCLODEXTRIN:N-ACETYLCYSTEINE COMPLEX.- LIPOPEPTIDES FROM BACILLUS SUBTILIS AC7 INHIBIT ADHESION AND BIOFILM FORMATION OF CANDIDA ALBICANS ON SILICONE.- NEW BISPHOSPHONATE MONOMERS AND POLYMERIC NANOPARTICLES FOR BIOMEDICAL APPLICATIONS: ANTIBACTERIALS AND INHIBITION OF BIOFILM FORMATION.- SIMPLE AND RAPID METHOD FOR DETECTING BIOFILM FORMING BACTERIA.- AN EFFICIENT ONE-POT SYNTHESIS OF THIOCHROMENO[3,4-D]PYRIMIDINES DERIVATIVES: INDUCING ROS DEPENDENT ANTIBACTERIAL AND ANTI-BIOFILM ACTIVITIES.

PART 2: PILONIDAL CYSTS AND SINUSES

HISTORY AND GENERAL INFORMATION ON PILONIDAL CYSTS AND SINUSES.- PILONIDAL DISEASE.- PILONIDAL SINUS DISEASE.- THERAPY OF PILONIDAL SINUS--IS MORE ALWAYS BETTER.- PILONIDAL SINUS: INCLUDING UMBILICAL PILONIDAL SINUS.- OPEN PILONIDAL WOUND TREATMENT.- THE EFFECT OF PHENOL CONCENTRATION ON THE TREATMENT OF PILONIDAL SINUS DISEASE.- CRYSTALLIZED OR LIQUID PHENOL APPLICATION IN PILONIDAL SINUS TREATMENT.- TOPICAL AGENTS AND DRESSINGS FOR PILONIDAL SINUS WOUND HEALING BY SECONDARY INTENTION.- MODIFIED OFF-MIDLINE CLOSURE OF PILONIDAL SINUS DISEASE.- CLEFT LIFT PROCEDURE FOR PILONIDAL DISEASE.- COMPARISON OF CONVENTIONAL INCISION AND DRAINAGE FOR PILONIDAL ABSCESS VERSUS NOVEL ENDOSCOPIC PILONIDAL ABSCESS TREATMENT.- LEARNING CURVE FOR PILONIDAL SINUS SURGERY.- RISK FACTORS FOR PILONIDAL SINUS DISEASE IN TEENAGERS.- COMPARISON OF TREATMENTS FOR AN INFECTED PILONIDAL SINUS: DIFFERENCES IN SCAR QUALITY AND OUTCOME BETWEEN SECONDARY WOUND HEALING AND LIMBERG FLAP.- MINIMAL EXCISION AND PRIMARY SUTURE IS A COST-EFFICIENT DEFINITIVE TREATMENT FOR PILONIDAL DISEASE WITH LOW MORBIDITY.- MINIMALLY INVASIVE SURGICAL APPROACH TO COMPLICATED RECURRENT PILONIDAL SINUS.- COMPARISON OF MIDLINE AND OFF-MIDLINE CLOSURE TECHNIQUES IN PILONIDAL SINUS SURGERY.- APPLICATION OF FASCIOCUTANEOUS V-Y ADVANCEMENT FLAP IN PRIMARY AND RECURRENT SACROCOCCYGEAL PILONIDAL SINUS DISEASE.- TANDEM RHOMBOID FLAP REPAIR: A NEW TECHNIQUE IN TREATMENT OF EXTENSIVE PILONIDAL DISEASE OF THE NATAL CLEFT.- CONSERVATIVE VS SURGICAL INTERVENTIONS FOR UMBILICAL PILONIDAL SINUS.