BOOKS BY CATEGORY
Your Account
Beneficial Effects of Perhexiline in Cardiovascular Disease States
This book is currently unavailable – please contact us for further information.
Price
Quantity
€46.07
(To see other currencies, click on price)
Paperback / softback
Add to basket  

MORE ABOUT THIS BOOK

Main description:

Perhexiline, 2-(2,2-dicyclohexylethyl) piperidine, was originally developed as a prophylactic anti-anginal drug in the late 1960s. It was initially a popular and effective treatment for angina, having the almost unique property compared to other agents available at that time, of not inducing reductions in blood pressure or heart rate. Despite the initial success, its use diminished markedly due to the occurrence during long-term therapy of poorly understood side effects (neurotoxicity and hepatotoxicity), which later were shown to be associated with high plasma concentrations of perhexiline, occurring in patients with relatively slow hepatic metabolism of the drug. However, therapeutic plasma monitoring and associated dose adjustments have led to perhexiline's reintroduction into clinical practice. This book discusses the benefits of perhexiline in the treatment of cardiovascular disease.


Contents:

Introduction; Clinical Applications of Perhexiline; Pharmacokinetics & Toxicity of Perhexiline; Pharmacology of Perhexiline; Conclusion & Future Perspectives; Index.


PRODUCT DETAILS

ISBN-13: 9781616689773
Publisher: Nova Science Publishers Inc
Publication date: October, 2010
Pages: None
Weight: 92g
Availability: Not available (reason unspecified)
Subcategories: Cardiovascular Medicine

CUSTOMER REVIEWS

Average Rating