Main description:

Bacterial diarrheal diseases are a very important problem for human health, and many people, especially infants and children, die every year from diarrheal diseases, particularly in developing countries. Thus, in 1978 the World Health Organization initiated a Diarrhoeal Diseases Control Programme and is now working actively to control diarrheal diseases. The "International Symposium on Bacterial Diarrheal Diseases" which took place in Osaka from March 23rd to 25th, 1982, was organized by Osaka University with the support of the Ministry of Education, Science and Culture of the Japanese Government. The aim of this Symposium was to promote exchange of scientific information on bacterial diarrheal diseases, few years due since studies in this field have progressed rapidly during the last to work in many laboratories throughout the world. It seems appropriate that this Symposium was held in Osaka, since during the past century Japanese bacteriologists have made a number of important con- tributions in the field of bacterial diarrheal diseases. Outstanding among these contributions are the recognition of Shigella as a causative agent of bacillary dysentery by Dr.
Kiyoshi Shiga and the serotyping of Vibrio cholerae into the Ogawa, Inaba and Hikojima serotypes by Drs. Kabeshima and Nobechi. Moreover more recently, Dr. Tsunesaburo Fujino of Osaka University discovered Vibrio parahaemolyticus as the causative agent of an important diarrheal disease.

Contents:

The Global Problem of Acute Diarrheal Diseases and the Who Diarrheal Diseases Control Programme.- The Vibrio Diseases in 1982: An Overview.- Epidemiology of Infantile Bacterial Diarrheal Disease in Brazil.- Epidemiology of Diarrhoeal Diseases in Bangladesh.- Epidemiology of Bacterial Enteric Pathogens in Rural Thailand: Application of a DNA Hybridization Assay to Detect Enterotoxigenic Escherichia Coli.- Epidemiology of Bacterial Diarrhoeal Diseases in India with Special Reference to Vibrio Parahaemolyticus Infections.- Etiological Study of Diarrheal Diseases in Shanghai.- Current Status of Bacterial Diarrheal Diseases in Japan.- Epidemiological Aspects of Campylobacter Enteritis.- Epidemiology of Salmonella and Shigella Infections in the United States.- The Cholera/Coli Family of Enterotoxins.- Recent Advances in the Study of Heat-Labile Enterotoxins of Escherichia Coli.- Heterogeneity of Enterotoxins of Vibrio Cholerae and Enterotoxigenic Escherichia Coli.- Internalization of Cholera Toxin Subunits into Mouse Thymus Cells.- Mechanism of Action of Choleragen: Effect of Toxin on Binding of Guanyl Nucleotides.- Cholera Toxin as a Mitotic Stimulator of Epidermal Cells In Vitro and In Vivo.- Secretory Immunity to Vibrio Cholerae Bacteria and Cholera Toxin: Prospects for an Improved Cholera Vaccine.- Molecular Heterogeneity of Vibrio Cholerae Non-O1 Enterotoxins.- Molecular Genetic Study on the Pathogenicity of an Enterotoxigenic Escherichia Coli Strain of Human Origin.- Increased Production of Heat-Labile Enterotoxin as a Result of TN3 Insertion into a Chimeric R/Ent Plasmid.- Evaluation of the Biken Test for the Detection of LT-Producing Escherichia Coli.- The Use of Germ-Free Mice Associated with Human Fecal Flora as an Animal Model to Study Enteric Bacterial Interactions.- Experimental Cholera in Piglet Models.- Campylobacter Enteritis.- Biochemical and Serological Characteristics and Fatty Acid Composition of Thermophilic Campylobacter.- Campylobacter Jejuni/Coli Serotyping in Developed and Developing Countries.- Drug Resistance of Shigella and Experimental Chemotherapy of Shigellosis.- The Pathogenesis of Bacillary Dysentery.- Ecology of Vibrio Cholerae, Vibrio Parahaemolyticus and Related Vibrios in the Natural Environment.- Pathogenesis of Vibrio Parahaemolyticus.- Author Index.