All 'you need to know' about the fast-changing area of anticoagulation. What's the disease? Venous thromboembolisim explained Who is at risk? How can high risk patients be identified? What are the established treatments? What are the new novel anticoagulants? Similarities, differences and uses? What are the current guidelines? What are the implications for primary care?
Introduction 1. Burden of venous and arterial thromboembolic (VAT) disease 2. Understanding haemostasis and thrombosis 3. Defining the high-risk patient 4. Antiplatelet therapies 5. Established anticoagulants 6. Novel anticoagulants: Direct thrombin inhibitors 7. Novel anticoagulants: Factor Xa inhibitors 8. Current clinical evidence for novel anticoagulants: Venous thromboembolism (VTE) 9. Current clinical evidence for novel anticoagulants: Stroke prevention in AF 10. Current clinical evidence for novel anticoagulants: Treatment of VTE 11. Current guidelines for clinical management 12. Implications for primary care 13. Antithrombotic therapy: The future 14. Conclusion Appendix: Practical guidance