Main description:

This book presents a collection of chapters describing the state of the art on computational modelling and fabrication in tissue engineering.

Tissue Engineering is a multidisciplinary field involving scientists from different fields. The development of mathematical methods is quite relevant to understand cell biology and human tissues as well to model, design and fabricate optimized and smart scaffolds.

The chapter authors are the distinguished keynote speakers at the first Eccomas thematic conference on Tissue Engineering where the emphasis was on mathematical and computational modeling for scaffold design and fabrication. This particular area of tissue engineering, whose goal is to obtain substitutes for hard tissues such as bone and cartilage, is growing in importance.

Contents:

Cell mechanics: The role of simulation , by Christopher R. Jacobs and Daniel J. Kelly; Multiscale Modelling of Bone Tissue - Remodelling and Application to Scaffold Design , by Helder C. Rodrigues, Pedro G. Coelho, Paulo R. Fernandes; Nonlinear Elastic Scaffold Design, Modeling and Fabrication for Soft Tissue Engineering, by Scott J. Hollister, Claire G. Jeong, J. Jakob Schwiedrzik, Anna G. Mitsak, Heesuk Kang, Francesco Migneco; Computational techniques for selection of biomaterial scaffolds for tissue engineering, by S Checa, C Sandino, DP Byrne, DJ Kelly, D Lacroix and PJ Prendergast; Modelling bone tissue engineering. The role of scaffold microstructural anisotropy on new bone tissue formation, by Jose A. Sanz-Herrera, Manuel Doblare and Jose M. Garcia-Aznar; Geometric modeling and analysis of bone micro-structures as a base for scaffold design , by Y. Holdstein, L. Podshivalov, A. Fischer; Electrospinning and Tissue Engineering, by Geoffrey R Mitchell and Fred Davis; Biofabrication Strategies for Tissue Engineering, by Paulo Jorge Bartolo, Marco Domingos, Tatiana Patricio, Stefania Cometa, Vladimir Mironov