Main description:

Ideal for students through to experimental biologists and health professionals dealing with the benefits and the failures of physiological and pathophysiological adaptations, this book dives into the role of the continuously changing natural environment on gene expression before relating back to modern day health conditions. It relays how gene expression is known to be modified by our (or by the modern) environment inclusive of factors such as gravity, altitude, temperature, air quality, physical conditioning as well as lifestyle, before applying this to how it impacts both health and disease conditions such as cardiac ischemia and cardiomyopathies, stroke, dementia, Alzheimer's, cancer, metal toxicity, etc.

Contents:

Preface
Acknowledgements
Contributing Authors
Adaptations in Disease States: Adaptive Protection Against NO Overproduction and Toxicity in Experimental Alzheimer's Disease
Maladaptive Myocardial Responses to Hypertension are Attenuated by Omega-3 Fatty Acids and Red Palm Oil Intake
Immunohistochemical Evaluation of the Adaptation of Growth Hormone Receptors in Benign Prostatic Hyperplasia and Prostate Carcinoma
Surfactant Protein D: Endogenous Adaptation Factor for Alveolar Macrophages in Microenvironment Changes
Self-Renewing Heart in the Era of Stem Cells: Who have saved the Heart of Prometheus?
Development and Adaptation in Diabetic Cardiomyopathy
Phosphodiesterase-5 Inhibition With Tadalafil Attenuates Detrimental Proteomic Changes in Type 2 Diabetic Myocardium
Biological Activities of Bacterial Levan and Three Fungal ?-glucans, Botryosphaeran and Lasiodiplodan, Under High Glucose Condition in the Pancreatic ?-cell Line INS-IE
Adaptation to Biological Rhythms and its Basis
Molecular Adaptations of Cancer Cells
Hydrogen Sulfide and Substance P in Acute Pancreatitis
Adaptations in Hypoxia/Ischemia: Novel Strategy for Adaptation to Hypoxia-Hyperoxia Improves Tolerance to Oxidative Stress and Hypoxia
Response of Mitochondrial Thiol-redox Systems to an Oxidant Challenge Caused by Acute Hypoxia: Protective Effect of Adaptation to Hypoxia/Hyperoxia
Astrocytes Are Key Players in Mediating Recovery Following Ischemic Stroke
Imaging the Penumbra: The Pathophysiologic Basis for Therapy of Ischemic Stroke
The Causal Contribution of Selective Blood-Brain Barrier to Glucose Transport in Brain Edema and Function Deterioration After Ischemia and Brain Injury
Mitochondrial ATP-Sensitive Potassium Channels Contribute to Cardiac Remodeling After Myocardial Infarction in Rats
Modeling Catecholaminergic Polymorphic Ventricular Tachycardia and Long-QT Syndrome using Induced Pluripotent Stem Cell-derived Cardiomyocytes
Cellular Mechanisms of Myocardial Ischemia
The Role of Oxidative Stress in the Induction of Transcription Factors at Different Stages of Adaptation to Hypoxia
Role of HIF-1? in Signaling Mechanisms of Urgent and Long-Term Adaptation in Different Regimens of Hypoxic Training
Impact of Altitude Training on Glucose Metabolism
Environment and Lifestyle Adaptations: Cardiac Adaptation in Athletes: Multimodality Imaging Assessment
Surface Electromyography: Technical Developments and Clinical Applications in Sports Medicine
Longitudinal Development of Physical Fitness Among Singaporean Youths: Insights and Lessons from Data Mining
Impact of Daily Physical Activity on the Health-Related Quality of Life and Academic Performance of Primary School Pupils in Singapore
Effects of Lower Body Positive Pressure on Cardiovascular Functions in Young Human Adults
Lifestyle-Related Risk Factors Alter Myocardial Response to Ischemia Via Interference with Cellular Adaptive Mechanisms
Development and Evaluation of Mechanical Counter Pressure Glove for Extravehicular Activity in Space
The Philosophy of Dementias
Challenges in the Neuropathological Diagnosis of Dementias
A Surgeons' Strategy to Create an In Vivo Bioreactor for Generation of Axially Vascularized Tissues and Organoids
Precursors of Interstitial Cells of Cajal in the Human Digestive Tract
Aging: Oxidative Stress and Senescent Cellular Phenotypes
Plant Adaptogens Stimulate Recovery and Survival After Exposure to Copper or Cadmium in Larvae of the Pond Snail Lymnaea Stagnalis
Index.