Main description:

This authoritative and important work returns for a second edition with updated chapters on production and regeneration of female and male germ cells, trophoblast, and the endometrium. New developments in hESC derivation that will impact clinical use are covered and cutting-edge technologies such as reprogramming and imprinting are addressed in relation to stem cells and reproductive medicine. New topics such as stem cells and their approach to male infertility treatment and actual clinical translation to IVF clinics from the stem cell perspective bring new depth to this concise textbook. The first edition established itself as the first book of its kind, this second edition now cements its reputation as a fascinating must-have resource for anyone working with reproductive medicine.

Contents:

1. Gamete Generation from Stem Cells: Will It ever Be Applicable? 2. Gamete Generation from Stem Cells: Will It ever Be Ethically Acceptable? 3. Molecular Biology of Gametes 4. Controlled Differentiation from ESC to Oocyte-like Cells 5. Germ Cell Specific Methylation Pattern 6. Germline Stem Cells and Adult Ovarian Function 7. Somatic Stem Cells Derived from Non-Gonadal Tissues 8. The Male Gamete 9. Growth Factor Signaling in Germline Specification and Maintenance of Stem Cell Pluripotency 10. Stem Cell Therapeutic Approaches for Treatment of Male Infertility 11. Adult Stem Cell Population in the Testes 12. Human Embryonic Stem Cells: A Model for Trophoblast Differentiation and Placental Morphogenesis 13. Reproductive Stem Cells of Embryonic Origin: Comparative Properties and Benefits 14. Amniotic Fluid and Placental Stem Cells 15. Adult Stem Cells in the Human Endometrium 16. Stem Cell Populations in Adult Bone Marrow 17. Models of Trophoblast Development and Embryo Implantation Using hESC 18. Embryo-Friendly Approaches to hESC Derivation 19. Reprogramming of Somatic Cells 20. Somatic Nuclear Transfer to In Vitro Matured Human Germinal Vesicle Oocytes 21. Derivation and Banking of hESC for Potential Clinical Use