Main description:

This volume gives a state-of-the-art overview on macrophage functions in various invertebrate and vertebrate systems and diseases. It also covers various aspects of macrophage development and formation, behavior and response to nano- and biomaterials, the latter of which have become very important components of modern medicine.

Macrophages are evolutionarily conserved phagocytotic cells. In recent years macrophages have emerged as one of the most versatile cells of immune system, which, depending on the milieu and circumstance, participate in development or inhibition of cancer, regeneration, wound healing, inflammation, organ rejection and interaction between mother and a fetus.

This book will be of particular interest to researchers working in immunology, cancer research, developmental biology, or related fields.

Contents:

A. Evolution, origin and fate of macrophages

1. Title: Evolutionary aspects of Macrophages polarizationAuthors: Eva-Stina Edholm, Kun Hyoe Rhoo, Jacques RobertCorresponding author: Jacques Roberte-mail: Jacques_Robert@urmc.rochester.edu
2. Title: Development and functional differentiation of tissue-resident vs. monocyte-derived macrophages in inflammatory reactionsAuthors: Paola Italiani and Diana Boraschi Corresponding author: Paola Italianie-mail: p.italiani@ibp.cnr.it
3. Title: Hofbauer cells - placental macrophages of fetal originAuthors: Leticia Reyes, Bryce Wolfe, Thaddeus GolosCorresponding author: Leticia Reyese-mail: Lreyes@wisc.edu
4. Title: Mesenchymal stem cells direct the immunological fate of macrophagesAuthors: Patricia Luz-Crawford, Christian Jorgensen, Farida DjouadCorresponding authors: Patricia Luz-Crawforde-mail: patricia.luzc@gmail.comFarida Djouade-mail: farida.djouad@inserm.fr 5. Title: Monocyte/Macrophage - NK cell Cooperation: Old Tools for New Functions Authors: Elzbieta Wlajtys-Rode and Jolanta M. Dzik Corresponding authors: Elzbieta Wlajtys-Rode e-mail: ewalajtys@ch.pw.edu.pl Jolanta W Dzike-mail: jolanta_dzik@sggw.pl
6. Title: Macrophages in non-vertebrates: from insects and crustaceans to marine bivalvesAuthors: Prasad Abnave, Xavier Muracciole and Eric Ghigo Corresponding author: Eric Ghigoe-mail: eric.ghigo@univ-amu.fr

B. Immunobiology of macrophages 7. Title: F4/80 as a Major Macrophage Marker: The case of the Peritoneum and SpleenAuthor: Alexandra dos Anjos CassadoCorresponding author: Alexandra dos Anjos Cassadoe-mail: alecassado@hotmail.com
8. Tile: Immunobiology of Nitric Oxide and Regulation of Inducible Nitric Oxide SynthaseAuthors: Martin Lee, Kevin Rey, Katrina Besler, Christine Wang, Jonathan ChoyCorresponding author: Jonathan Choye-mail: jonathan.choy@sfu.ca
9. Title: Role for mechanotransduction in macrophage and dendritic cell immunobiologyAuthors: Svenja F. B. Mennens, Koen van den Dries, Alessandra CambiCorresponding author: Alessandra Cambie-mail: Alessandra.Cambi@radboudumc.nl

C. Role of macrophages in disease10. Title: Macrophages' Role in Tissue Disease and RegenerationAuthors: Lewis Gaffney, Paul Warren, Emily A. Wrona, Matthew B. Fisher, Donald O. FreytesCorresponding authors: Matthew B. Fishere-mail: mbfisher@ncsu.eduDonald O. Freytes e-mail: dofreyte@ncsu.edudfreytes@unc.edu
11. Title: Macrophages and their contribution to the development of atherosclerosisAuthors: Yuri V. Bobryshev, Nikita G. Nikiforov, Natalia V. Elizova, Alexander N. Orekhov Corresponding author: Yuri V. Bobrysheve-mail: y.bobryshev@mail.ru y.bobryshev@unsw.edu.au
12. Title: Macrophage Dysfunction in Respiratory DiseaseAuthors: Kylie B. R. Belchamber, Louise E. DonnellyCorresponding author: Louise E. Donnellye-mail: l.donnelly@imperial.ac.uk
14. Title: Macrophage differentiation in normal and accelerated wound healingAuthors: Girish J. Kotwal, Sufan ChienCorresponding authors:Girish J. Kotwale-mail: GJKOTW01@gmail.comSufan Chiene-mail: Sufan.Chien@louisville.edu
15. Title: Macrophages and RhoA pathway in transplanted organs Authors: Yianzhu Liu, Jacek Z Kubiak, Xian C. Li, Rafik M Ghobrial, Malgorzata Kloc Corresponding author: Malgorzata Kloce-mail: mkloc@houstonmethodist.org