Main description:

Today's bioimaging technologies generate mountains of biological data that can simply overwhelm conventional analysis methods. This groundbreaking book helps researchers blast through the computational bottleneck with high-performance computing (HPC) techniques that are blazing the way to never-before bioimaging, image analysis, and data mining capabilities and revolutionizing the study of cellular and organ-level systems. This innovative volume surveys the latest advances in scanning electron microscopy, knife-edge scanning microscopy, and 4D imaging of multi-component biological systems. The book includes detailed case studies that show how key techniques have been successfully deployed in medical image analysis, drug discovery, tissue analysis, functional MRI data analysis, and other areas.

Contents:

Image Acquisition I: Serial Block Face Scanning Using High-Resolution Scanning Electron Microscopy.; Image Acquisition II: Knife-Edge Scanning Microscope.; Image Acquisition III: 4D Imaging of Multi-Component Biological Systems.; 4D Image Analysis I: Feature Extraction on Parallel Machines.; 4D Image Analysis II: Parallel Data Mining. gridImage Microscopy. High-Throughput Image-Based Screening. Laser Capture Microdissection. Applications of High-Performance Computing to Functional Magnetic Resonance Imaging (fMRI) Data. Databases for Bioimaging. Interactive Visualization of Large Image Datasets. Conclusion.