Main description:

This volume stems from the Second International Conference on Environmental Stressors in Biology and Medicine, which occurred October 5-7, 2011 in Siena, Italy. Included are short reviews and perspectives on the basic mechanisms of environmental stressors; physical and chemical stressors and related diseases; air pollutants and related diseases; protection afforded by food and pharmaceuticals; and food as a source of stressors. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Contents:

Omics approaches in cystic fibrosis research: a focus on oxylipin profiling in airway secretions Jason P. Eiserich Jun Yang Brian M. Morrissey Bruce D. Hammock Carroll E. Cross 1

Nitric oxide signaling in the brain: translation of dynamics into respiration control and neurovascular coupling Joao Laranjinha Ricardo M. Santos Catia F. Lourenco Ana Ledo RuiM. Barbosa 10

Physiological functions of GPx2 and its role in inflammation-triggered carcinogenesis Regina Brigelius-Flohe Anna Patricia Kipp 19

Molecular medicine and the development of cancer chemopreventive agents Alberto Izzotti 26

Experimental basis for discriminating between thermal and athermal effects of water-filtered infrared A irradiation Tobias Jung Tilman Grune 33

Acrolein effects in pulmonary cells: relevance to chronic obstructive pulmonary disease Nadia Moretto Giorgia Volpi Fiorella Pastore Fabrizio Facchinetti 39

Sarcopenia and smoking: a possible cellular model of cigarette smoke effects on muscle protein breakdown Oren Rom Sharon Kaisari Dror Aizenbud Abraham Z. Reznick 47

The link between altered cholesterol metabolism and Alzheimer's disease Paola Gamba Gabriella Testa Barbara Sottero Simona Gargiulo Giuseppe Poli Gabriella Leonarduzzi 54

Rottlerin and curcumin: a comparative analysis Emanuela Maioli Claudia Torricelli Giuseppe Valacchi 65

Plant polyphenols and human skin: friends or foes Liudmila Korkina Chiara De Luca Saveria Pastore 77

Flavonoids and metabolic syndrome Monica Galleano Valeria Calabro Paula D. Prince Maria C. Litterio Barbara Piotrkowski Marcela A. Vazquez-Prieto Roberto M. Miatello Patricia I. Oteiza Cesar G. Fraga 87

Dietary polyphenols in cancer prevention: the example of the flavonoid quercetin in leukemia Carmela Spagnuolo Maria Russo Stefania Bilotto Idolo Tedesco Bruna Laratta Gian Luigi Russo 95

Cigarette smoke and ozone effect on murine inflammatory responses Concetta Gardi Giuseppe Valacchi 104

Age-related changes in cellular protection, purification, and inflammation-related gene expression: role of dietary phytonutrients Angela Mastaloudis Steven M. Wood 112

The role of oxidative stress in Rett syndrome: an overview Claudio De Felice Cinzia Signorini Silvia Leoncini Alessandra Pecorelli Thierry Durand Giuseppe Valacchi Lucia Ciccoli Joussef Hayek 121

Emerging topics in cutaneous wound repair Giuseppe Valacchi Iacopo Zanardi Claudia Sticozzi Velio Bocci Valter Travagli 136

Corrigendum for Ann. N.Y. Acad. Sci. 1236: 30-43 145