Main description:

Written with useful practicality in mind, Breast Pathology, 3rd Edition, provides surgical pathologists with authoritative guidance on the selection and best use of proper diagnostic techniques when reporting on breast specimens. Dr. David J. Dabbs and a team of internationally acclaimed pathologists incorporate genomic and molecular information, gross and microscopic findings, radiologic and laboratory diagnosis, theranostics, and immunohistochemistry to cover every aspect of benign and malignant lesions of the breast, helping you minimize diagnostic variation and error in the sign-out room.

Brings you fully up to date with recent advances, including new molecular information for breast entities, new surgical techniques, more widely used multigene prognostic tests, and assays used to determine treatment, such as PD-L1 as a new immunotherapy biomarker for triple-negative breast cancer.

Incorporates the latest classifications of breast pathology and molecular diagnosis.

Organizes each topical chapter around relevant genomic and molecular information, clinical presentation, gross and microscopic pathologic findings and diagnostic and molecular immunohistochemistry.

Maps immunohistochemistry for each entity according to diagnostic, theranostic, and genomic applications, with specific regard to disease entities in each chapter.

Discusses breast specimen handling in detail to assure proper sampling and processing for optimal molecular and immunohistochemistry resulting.

Supplies a convenient quick reference at the beginning of each chapter that includes all relevant diagnostic, theranostic, and genomic data for fast retrieval.

Features approximately 2,000 full-color pathological images that clearly depict clinical, radiological, molecular, immunohistochemical, and theranostic aspects of disease.

Includes biomarker guideline updates throughout.

Reflects updates to new tumor staging data in the American Joint Committee on Cancer (AJCC) 8th Edition and updated ASCO/CAP guidelines for interpreting HER2 assays.

Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Contents:

Normal Breast and Developmental Disorders
Reactive and Inflammatory Conditions of the Breast
Infections of the Breast
Epidemiology of Breast Cancer and Pathology of Heritable Breast Cancer
Patient Safety in Breast Pathology
Gross Examination of Breast Specimens
Sentinel Lymph Node Biopsy
Breast Imaging Modalities for Pathologists
Predictive and Prognostic Marker Testing in Breast Pathology: Immunophenotypic Subclasses of Disease
Molecular-Based Testing in Breast Disease for Therapeutic Decisions
Diagnostic Immunohistology of the Breast
Fibroepithelial Lesions
Papilloma and Papillary Lesions
Adenosis and Microglandular Adenosis
Nipple Adenoma (Florid Papillomatosis of the Nipple)
Radial Scar
Myoepithelial Lesions of the Breast
Fibrocystic Change and Usual Epithelial Hyperplasia of Ductal Type
Columnar Cell Alterations, Flat Epithelial Atypia, and Atypical Ductal Epithelial Hyperplasia
Molecular Classification of Breast Carcinoma
Lobular Neoplasia and Invasive Lobular Carcinoma
Ductal Carcinoma In Situ
Invasive Ductal Carcinoma of No Special Type and Histologic Grade
Triple-Negative and Basal-like Carcinoma
Metaplastic Breast Carcinoma
Apocrine Carcinoma of the Breast
Paget Disease of the Breast
Pathology of Neoadjuvant Therapeutic Response of Breast Carcinoma
Special Types of Invasive Breast Carcinoma: Tubular Carcinoma, Mucinous Carcinoma, Cribriform Carcinoma, Micropapillary Carcinoma, Carcinoma with Medullary Features
Rare Breast Carcinomas: Adenoid Cystic Carcinoma, Neuroendocrine Carcinoma, Secretory Carcinoma, Carcinoma with Osteoclast-like Giant Cells, Lipid-Rich Carcinoma, and Glycogen-Rich Clear Cell Carcinoma
Mesenchymal Neoplasms of the Breast
Neoplasia of the Male Breast
Breast Tumors in Children and Adolescents
Tumors of the Mammary Skin
Hematopoietic Tumors of the Breast
Metastatic Tumors in the Breast
Next-Generation DNA Sequencing and the Management of Patients with Clinically Advanced Breast Cancer