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Main description:
Expert physicians and clinical researchers summarize and explain all the recent advances in the biology and treatment of bone marrow-based malignancy. On the biological side, the authors show the characteristics of the malignant cell and describe the significant roles played by oncogenic changes, chromosomal anomalies, Kaposi's sarcoma herpes virus, and cytokines. New epidemiological findings and prognostic factors are also analyzed. On the clinical side, the authors provide a comprehensive review of conventional treatment regimens, as well as a discussion of newer experimental approaches involving immunologic targeting, inhibitors of drug resistance, and antitumor agents.
Contents:
Diagnosis of Multiple Myeloma
Robert A. Kyle and Daniel E. Bergsagel
Epidemiology of Multiple Myeloma and Related Disease
Brian G. M. Durie
Characterization of the Myeloma Clone
Robert A. Vescio and James R. Berenson
Oncogenesis of Multiple Myeloma
Johannes Drach, Sonja Seidl, Jutta Ackermann, and Hannes Kaufmann
Cytokines in Multiple Myeloma
John De Vos and Bernard Klein
Monoclonal Gammopathy of Undetermined Significance
Robert A. Kyle
Tumor Burden: Staging and Prognostic Factors
Douglas E. Joshua
Treatment of Multiple Myeloma
Meletios A. Dimopoulos and Robert A. Kyle
Dose-Intensive Therapy With Autologous Stem Cell Transplantation for Patients With Multiple Myeloma
Jean-Luc Harousseau, Michel Attal, and Gary J. Schiller
Allogeneic Transplantation in Multiple Myeloma
Goesta Gahrton, Kenneth C. Anderson, and William Bensinger
Immunological Approaches to Multiple Myeloma
Hakan Mellstedt, Maurizio Bendandi, Anders OEsterborg, and Larry W. Kwak
Remission Maintenance in Multiple Myeloma
Heinz Ludwig and Niklas Zojer
Myeloma Bone Disease
James R. Berenson
Renal Diseases Associated With Multiple Myeloma and Related Plasma Cell Dyscrasias
Alan Solomon, Deborah T. Weiss, and Guillermo A. Herrera
Pathogenesis and Treatment of Anemia
Heinz Ludwig and Anders OEsterborg
New Therapeutic Approaches to Myeloma
Terry H. Landowski, William S. Dalton, and Sydney E. Salmon
Index
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: November, 2010
Pages: 378
Weight: 614g
Availability: Available
Subcategories: Haematology
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