Published June, 2018
By Yuzhuo Wang, Dong Lin and Peter W. Gout
Publisher: Springer (Birkhauser Verlag AG)
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By Yuzhuo Wang, Dong Lin and Peter W. Gout
Publisher: Springer (Birkhauser Verlag AG)
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In separately produced chapters, the history and evolution of PDX models is reviewed, methods of PDX model development are compared in detail, characteristics of available established models are presented, current applications are summarized and new perspectives about use of PDX models are proposed.
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€102.39
Published June, 2018
By Giuseppe Di Giovanni, Ferdinando Nicoletti, Richard Teke Ngomba and Giuseppe Battaglia
Publisher: Springer (Birkhauser Verlag AG)
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By Giuseppe Di Giovanni, Ferdinando Nicoletti, Richard Teke Ngomba and Giuseppe Battaglia
Publisher: Springer (Birkhauser Verlag AG)
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Metabotropic glutamate receptors (mGluRs) are members of the group C family of G-protein-coupled receptors. Eight different mGlu subtypes have been identified and classified into three groups based on amino acid sequence similarity, agonist pharmacology, and the signal transduction pathways to which they couple.
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€191.99
Published June, 2018
By Taner Demirer
Publisher: Springer (Birkhauser Verlag AG)
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By Taner Demirer
Publisher: Springer (Birkhauser Verlag AG)
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This book discusses the aspects of haploidentical transplants and will shed light on the debates and questions on this burgeoning field and timely topic.
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€166.39
Published June, 2018
By Philip W. Hinds and Nelson E. Brown
Publisher: Springer (Birkhauser Verlag AG)
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By Philip W. Hinds and Nelson E. Brown
Publisher: Springer (Birkhauser Verlag AG)
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This volume provides an integrated account of our current understanding of the functions of D-type cyclins during development and tumorigenesis, with special emphasis on the kinase-independent functions of these proteins.
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€166.39
Published June, 2018
By Kevin T. McVary and Tobias S. Koehler
Publisher: Springer (Birkhauser Verlag AG)
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By Kevin T. McVary and Tobias S. Koehler
Publisher: Springer (Birkhauser Verlag AG)
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New chapters in this edition discuss the profound effects oflifestyle change on sexual function, alternative and internet drugs that affectsexual function, endovascular approaches to ED, penile length considerations,the effect of radiation on erectile function, and optimizing ED research.
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€102.39
Published June, 2018
By Marc Damelin
Publisher: Springer (Birkhauser Verlag AG)
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By Marc Damelin
Publisher: Springer (Birkhauser Verlag AG)
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While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties.
Hardback
€166.39
Published June, 2018
By Essam M. Abdelalim
Publisher: Springer (Birkhauser Verlag AG)
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By Essam M. Abdelalim
Publisher: Springer (Birkhauser Verlag AG)
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This volume explores recent advances in the use of pluripotent stem cells (PSCs) and adult stem cells (ASCs) in basic and clinical applications.
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€179.19
Published June, 2018
By Philip B. Gorelick and Venkatesh Aiyagari
Publisher: Springer (Birkhauser Verlag AG)
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By Philip B. Gorelick and Venkatesh Aiyagari
Publisher: Springer (Birkhauser Verlag AG)
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€127.99
Published June, 2018
By Nicola Curtin and John Pollard
Publisher: Springer (Birkhauser Verlag AG)
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By Nicola Curtin and John Pollard
Publisher: Springer (Birkhauser Verlag AG)
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As a result of all these observations there has been a great interest in targeting the DDR to provide anti-cancer agents that may have benefit as monotherapy in cancers with high background DNA damage levels or as a means to increase the efficacy of DNA damaging drugs and IR.
Hardback
€230.39
Published May, 2018
By Brian Leyland-Jones, Nandini Dey and Pradip De
Publisher: Springer (Birkhauser Verlag AG)
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By Brian Leyland-Jones, Nandini Dey and Pradip De
Publisher: Springer (Birkhauser Verlag AG)
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Paperback / softback
€191.99