The TNM Supplement , 4th Edition, includes new, detailed definitions of anatomical sites, regional lymph nodes, and TNM categories. It answers questions that frequently arise during daily use of the TNM system. Importantly, the TNM Supplement expands on the minimum requirements for pathological classification of individal tumour sites and enumerates the recommended criteria for each. Published in association with the Union for International Cancer Control, it provides oncologists with complementary material related to TNM staging not covered in TNM Classification of Malignant Tumours, 7th Edition .
Preface, viii Organizations Associated with the TNM System, xiii National Committees, xiii Acknowledgements, xiv Abbreviations, xv Chapter 1 EXPLANATORY NOTES - GENERAL The General Rules of the TNM System, 1 The TNM Clinical and Pathological Classifications, 6 Residual Tumour (R) Classification, 14 Additional Descriptors, 18 Unknown Primary, 22 Staging of Tumours for Which No TNM Classification is Provided, 22 Histopathological Grading, 23 Chapter 2 EXPLANATORY NOTES - SPECIFIC ANATOMICAL SITES Head and Neck Tumours, 30 Lip and Oral Cavity, 37 Digestive System Tumours, 46 Lung and Pleural Tumours, 69 Bone Tumours, 81 Soft Tissue Tumours, 82 Skin Tumours, 83 Breast Tumours, 89 Gynaecological Tumours, 92 Urological Tumours, 101 Kidney, 105 Adrenal Cortex Tumours 109 Ophthalmic Tumours 110 Hodgkin Lymphoma and Non-Hodgkin Lymphomas, 116 Appendix, 118 Chapter 3 SITE-SPECIFIC REQUIREMENTS FOR pT AND pN Introduction, 134 Head and Neck Tumours, 136 Digestive System Tumours, 142 Lung and Pleural Tumours, 148 Tumours of Bone and Soft Tissues, 150 Skin Tumours, 151 Breast Tumours, 154 Gynaecological Tumours, 156 Urological Tumours, 159 Adrenal Cortex Tumours, 164 Ophthalmic Tumours, 165 Hodgkin Lymphoma and Non-Hodgkin Lymphomas, 167 Chapter 4 NEW TNM CLASSIFICATIONS RECOMMENDED FOR TESTING Introduction, 171 General, 171 Specific, 171 Gastrointestinal Sarcomas (other than GISTs) (ICD-O C15-21), 172 Malignant Thymic Epithelial Tumours (Thymoma) (ICD-O C37), 174 Cranial and Facial Bones (ICD-O C41.0, 1), 174 Primary Cutaneous Lymphomas, 177 Cutaneous T-Cell Lymphoma (Excluding Lip, Eyelid, Vulva and Penis) (ICD-0 C44.2-7, C63.2), 177 ISLC/EORTC Revision to the Classification of Mycosis Fungoides and Sezary Syndrome, 180 Chronic Myeloid Leukaemia, 182 Multiple Myeloma, 185 Primary Liver Carcinoma in Infants and Children/Hepatoblastoma, 186 Adrenal Cortex Carcinoma, 188 Liver Metastasis of Colorectal Carcinoma, 188 Gastrointestinal Malignant Lymphomas, 189 Chapter 5 OPTIONAL PROPOSALS FOR TESTING NEW TELESCOPIC RAMIFICATIONS OF TNM All Tumour Sites, 193 Head and Neck Tumours, 193 Digestive System Tumours, 193 Liver, 196 Lung Tumours, 196 Tumours of Bone and Soft Tissues, 198 Gynaecological Tumours, 198 Urological Tumours, 199 Chapter 6 FREQUENTLY ASKED QUESTIONS General Questions, 202 Site-Specific Questions, 211 Index, 243 Plate section facing p. 48