This book presents a state-of-the-art review of the latest advances in developing calcium- phosphate bone cements and their applications. It covers the synthesis methods, characterization approaches, material modification and novel binders, as well as the fabrication technologies of calcium-phosphate-based biomaterials in regenerative medicine and their clinical applications. It also highlights methodologies for fabricating scaffolds, biofunctional surfaces/interfaces and subsequently modulating the host response to implantable/injectable materials, and integrates a series of discussions and insights into calcium-phosphate cements and constructs in bone regenerative medicine. As such, the book not only covers the fundamentals but also opens new avenues for meeting future challenges in research and clinical applications.
Calcium Phosphate Bone Cements: Their Development and Clinical Applications.- Self-Setting Calcium Orthophosphate (CaPO4) Formulations.- Injectable Calcium Phosphate Cements for Hard Tissue Repair.- Calcium Phosphate Composite Cement.- Accelerating Biodegradation of Calcium Phosphate Cement.- Bioactivation of Calcium Phosphate Cement by Growth Factors and Their Applications.- Drug-Loading Calcium Phosphate Cements for Medical Applications.- Biomimetic Ion-Substituted Calcium Phosphates.- Nanodimensional and Nanocrystalline Calcium Orthophosphates.- Calcium Phosphate-Silk Fibroin Composites: Bone Cement and Beyond.- Importance of Biomaterials in vivo Microenvironment pH (Î¼e-pH) in the Regeneration Process of Osteoporotic Bone Defects.- 3D-Printing of Calcium Phosphate Bio-Scaffolds for Bone Therapy and Regeneration.- Development of Biodegradable Bone Graft Substitutes Using 3D Printing.- Preparation of Collagen/Calcium Phosphate Coatings and Evaluation of Their Biological Performances.- Preclinical and Clinical Assessments of Calcium Phosphate Bone Cements.