Published March, 2010
By Yves Christen and Suzanne Craft
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Research and Perspectives in Alzheimer's Disease
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Availability: Available

This text provides a broad survey of the role of insulin in the brain. And it discusses the mechanisms through which insulin dysregulation contributes to the development of cognitive impairment and late-life neurodegenerative disease.

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Published December, 2008
By Yves Christen, Peter H. George-Hyslop, William C. Mobley and Peter H. St.George-Hyslop
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Research and Perspectives in Alzheimer's Disease
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Availability: Available

Many adult onset neurodegenerative diseases arise from the accumulation of misfolded peptides. This book examines the role sub-cellular trafficking pathways play in the pathological accumulation of these misfolded proteins and in attempts to clear them.

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Published January, 2008
By Yves Christen, Dennis J. Selkoe and Antoine Triller
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Research and Perspectives in Alzheimer's Disease
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Availability: Available

A biochemical hypothesis - that Alzheimer's disease (AD) is a progressive cerebral amyloidosis caused by the aggregation of the amyloid b-protein (Ab) - preceded and enabled the discovery of etiologies.

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Published October, 2006
By Konrad Beyreuther, Mathias Jucker, Christian Haass, Roger M. Nitsch and Christen Yves
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Research and Perspectives in Alzheimer's Disease
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Availability: Available

Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4, 1906 in Tubingen. The celebratory event "Alzheimer 100 Years and Beyond" was organized through the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen.

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