Published October, 2010
By B. W. J. Mahy
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

Foot-and-mouth disease (FMD) has been recognized in printed records dating from the sixteenth century, and since the eradication of rinderpest (cattle plague) in the early part of the twentieth century it has been rec- nized as the most important and feared disease of cattle and other dom- tic livestock.

---

Published October, 2010
By Riccardo Dalla-Favera and Federico Caligaris-Cappio
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

For a long time the Cinderella of lymphoid malignancies CLL has now become the focus of major interest and an increasing number of investigators from different areas, including genetics, molecular biology, basic and applied immunology are becoming actively engaged in the investigation of CLL.

---

Published October, 2010
By Sanjeev Krishna and David Sullivan
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

Despite rapid increases in knowledge, malaria continues to kill more than a million people each year and causes symptomatic disease in a further 300 million individuals. This volume brings some of the world's best investigators to describe recent advances in both the scientific and clinical aspects of malaria, and bridges between the two.

---

Published October, 2010
By Patrice Boquet and E. Lemichez
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

Pathogenic bacteria for human and animals have developed sophisticated weapons, termed virulence factors, to ensure their replication and persistence into their hosts. The authors in this volume show a synthesis on how the various host cellular Rho GTPases activities are manipulated by bacteria to fulfil their virulence.

---

Published October, 2010
By Klaus Aktories, K. Aktories and T.D. Wilkins
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

Clostridium difficile has been recognized as the cause of a broad spectrum of enteric disease ranging from mild antibiotic-associated diarrhea to pseudomembranous colitis.

---

Published October, 2010
By Luis Enjuanes
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

Human coronaviruses caused the SARS epidemic that infected more than 8000 people, killing about ten percent of them in 32 countries. This book provides essential information on these viruses and the development of vaccines to control coronavirus infections.

---

Published October, 2010
By Christian Rommel, Bart Vanhaesebroeck and Peter K. Vogt
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

PI3K has become a very intense area of research, with over 2000 publications on PI3K in PubMed for 2009 alone. The expectations for a therapeutic impact of intervention with PI3K activity are high, and progress in the clinical arena is being monitored by many.

---

Published October, 2010
By Christian Rommel, Bart Vanhaesebroeck and Peter K. Vogt
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress.

---

Published September, 2010
By M. Celeste Simon
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

Although severe hypoxia is generally toxic for both normal tissue and tumors, neoplastic cells gradually adapt to prolonged hypoxia though additional genetic and genomic changes with a net result that hypoxia promotes tumor progression and therapeutic resistance.

---

Published September, 2010
By John E. Johnson
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
Rating:
Availability: Available

The means by which non-enveloped viruses penetrate cellular membranes during cell entry remain poorly defined.

---