Main description:

Translational Neuroimmunology: Multiple Sclerosis provides an update on bench to bedside studies on Multiple Sclerosis as an autoimmune disease. Divided into twelve chapters, the book begins with an in-depth introduction to the neuroimmunology and immunopathology of multiple sclerosis. Sections also provide content on genetics and epigenetics, the microbiome, diagnosis, and treatment of multiple sclerosis. Finally, various precision treatments are covered. All information is presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research.

Contents:

1. Introduction on the Neuroimmunology of Multiple Sclerosis 2. Immunopathology of multiple sclerosis 3. Biomarkers of multiple sclerosis 4. Translational research into the pathogenesis of secondary progressive multiple sclerosis 5. Neuroimmunology of fatigue in multiple sclerosis 6. Microbiome and multiple sclerosis 7. Interaction with parasites and herpesviruses in people with multiple sclerosis - potential applications for prevention and treatment 8. Cytotoxic cells in multiple sclerosis: new targets for treatment 9. Targeting leukocytes in multiple sclerosis: therapeutic perspectives 10. Antibodies and antibody fragments developed for treatment of multiple sclerosis 11. Sphingosine-1-Phosphate, its Receptors, and their Role in Multiple Sclerosis, an Inflammatory and Autoimmune Disease of the Central Nervous Systems 12. Innate and adaptive immunomodulation by burton tyrosine kinase (BTK) inhibitors: review of emerging multiple sclerosis treatment