Main description:

In this issue of Hematology/Oncology Clinics, guest editors Drs. Sophie Lanzkron and Jane Little bring their considerable expertise to the topic of Sickle Cell Syndromes. Top experts in the field cover key topics such as structural racism and impact on sickle cell disease (SCD); pathophysiology and biomarkers of SCD; genetic modifiers of SCD; allogeneic transplant and gene therapy: reproductive health; chronic pain; and more.

Contains 16 relevant, practice-oriented topics including innovative therapies, addressing challenging complications, novel science on mechanisms of disease; preventing cognitive decline in people with SCD; quality of life in SCD; and more.

Provides in-depth clinical reviews on sickle cell syndromes, offering actionable insights for clinical practice.

Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Contents:

Structural Racism and Impact on Sickle Cell Disease: Sickle Cell Lives Matter
Sickle Cell Disease Pathophysiology and Related Molecular and Biophysical Biomarkers
Genetic Modifiers of Sickle Cell Disease
Economics of Sickle Cell Disease and Evidence to Support Comprehensive Care
Quality of Life in Sickle Cell Disease: What Matters
Chronic Pain: Prevalence and Management
The Development of Neuroimaging Biomarkers for Cognitive Decline in Sickle Cell Disease
Clinical Vignettes Part I
Clinical Vignettes Part II
The Cardiopulmonary Complications of Sickle Cell Disease
Sickle Cell Disease and the Kidney: Filters Gone Awry
Go the Distance: Reproductive Health Care for People with Sickle Cell Disease
Genotyping and the Future of Transfusion in Sickle Cell Disease
The Evolving Landscape of Drug Therapies for Sickle Cell Disease
Allogeneic Transplant and Gene Therapy: Evolving Toward a Cure